{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:41:16Z","timestamp":1791124876977,"version":"4.1.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T00:00:00Z","timestamp":1728086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100017594","name":"Medical Science and Technology Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2020KY191"],"award-info":[{"award-number":["2020KY191"]}],"id":[{"id":"10.13039\/501100017594","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the 1\u2010year effects of orthokeratology (OK) lenses and spectacle lenses with highly aspherical lenslets (HALs) on axial length (AL) elongation in children with unilateral myopic anisometropia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This ambispective cohort study recruited 81 children aged 8\u201314\u2009years with unilateral myopic anisometropia. Of these, 42 participants (mean age 11.07\u2009\u00b1\u20091.54\u2009years; 23 males) were treated with monocular OK lenses (OK group), and 39 (mean age 10.64\u2009\u00b1\u20091.72\u2009years; 22 males) with binocular HALs (HAL group). Changes in AL and spherical equivalent refraction (SER) from baseline at 3, 6 and 12\u2009months were compared between eyes and groups. Kaplan\u2013Meier estimation and Cox proportional hazard regression were performed to analyse the risk of myopia onset in the initially non\u2010myopic eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean axial elongation in the myopic and non\u2010myopic eyes at the 12\u2010month follow\u2010up visit were 0.17\u2009\u00b1\u20090.20 and 0.41\u2009\u00b1\u20090.26\u2009mm in the OK group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and 0.10\u2009\u00b1\u20090.15 and 0.12\u2009\u00b1\u20090.12\u2009mm in the HAL group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.32), respectively. Compared with the OK group, the non\u2010myopic eyes in the HAL group had less axial elongation, lower cumulative myopia incidence and percentage of participants with rapid myopic shift at the 6\u2010 and 12\u2009month follow\u2010up (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Cox regression analysis showed that a higher initial SER decreased the risk of myopia onset significantly in the initially non\u2010myopic eyes (\n                      <jats:italic>B<\/jats:italic>\n                      \u2009=\u2009\u22122.06; 95% CI, 0.03\u20130.49;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Monocular OK lenses suppressed axial elongation in the myopic eye and minimised anisometropia; however, the non\u2010treated contralateral eye may experience faster myopia onset and myopic shift. Binocular HALs can effectively reduce axial elongation in both eyes of children with unilateral myopic anisometropia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13388","type":"journal-article","created":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T11:24:16Z","timestamp":1728127456000},"page":"1407-1413","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effects of orthokeratology and spectacle lenses with highly aspherical lenslets on unilateral myopic anisometropia control"],"prefix":"10.1007","volume":"44","author":[{"given":"Jing","family":"Zhai","sequence":"first","affiliation":[{"name":"National Clinical Research Center for Ocular Diseases, Eye Hospital Wenzhou Medical University  Wenzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Fang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Ocular Diseases, Eye Hospital Wenzhou Medical University  Wenzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunjie","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Ocular Diseases, Eye Hospital Wenzhou Medical University  Wenzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengli","family":"Lian","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Ocular Diseases, Eye Hospital Wenzhou Medical University  Wenzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijie","family":"Hou","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Ocular Diseases, Eye Hospital Wenzhou Medical University  Wenzhou Zhejiang 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