{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T17:55:34Z","timestamp":1779126934256,"version":"3.51.4"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2025,1]]},"abstract":"Abstract<\/jats:title>\n \n Purpose<\/jats:title>\n To determine how corneoscleral geometry changes with axial length and to assess the usefulness of including the sagittal configuration of the anterior segment when predicting the axial length.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n An observational study was performed including 96 healthy subjects (96 eyes). Axial length was calculated from optical biometry (IOL Master 500). Corneal curvature and scleral sagittal height parameters at 13, 14 and 15\u2009mm were obtained automatically using corneoscleral topography (eye surface profiler; ESP). In addition, corneal and scleral sagittal heights at numerous locations (21 radii: 0\u201310\u2009mm from the corneal apex at 12 angles: 0\u2013330\u00b0) were calculated using the raw height data extracted from the ESP. The relationships between axial length and the study parameters were analysed using Pearson correlation analysis. The equations for the prediction of axial length were obtained by fitting multiple linear regression models.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The temporal\u2010nasal scleral asymmetry at 13\u2010, 14\u2010 and 15\u2010mm chord lengths was significantly correlated with axial length (\n r<\/jats:italic>\n 2<\/jats:sup>\n \u2009\u2264\u20090.26;\n p<\/jats:italic>\n \u2009<\u20090.001). Significant inverse correlations were found between the temporal scleral sagittal height and axial length (\n r<\/jats:italic>\n 2<\/jats:sup>\n \u2009\u2264\u20090.28;\n p<\/jats:italic>\n \u2009\u2264\u20090.02). The nasal scleral sagittal height was not associated with axial length. Three significant multiple linear regression models were fitted based on spherical equivalent, corneal radius and scleral asymmetry at 13 (\n r<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.79;\n p<\/jats:italic>\n \u2009<\u20090.001), 14 (\n r<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.80;\n p<\/jats:italic>\n \u2009<\u20090.001) and 15 (\n r<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.80;\n p<\/jats:italic>\n \u2009<\u20090.001) mm chord lengths.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Larger ocular globes show reduced temporal\u2010nasal scleral asymmetry, mainly due to the lower sagittal height of the temporal sclera. Thus, the geometry of the temporal scleral may be a factor of interest during myopia progression.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/opo.13402","type":"journal-article","created":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T11:44:28Z","timestamp":1727955868000},"page":"152-159","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Axial length association with corneoscleral sagittal height and scleral asymmetry"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3765-2478","authenticated-orcid":false,"given":"Elena","family":"Mart\u00ednez\u2010Plaza","sequence":"first","affiliation":[{"name":"Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy University of Alicante Alicante Spain"},{"name":"University of Valladolid Valladolid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6017-8618","authenticated-orcid":false,"given":"Alberto","family":"L\u00f3pez\u2010de la Rosa","sequence":"additional","affiliation":[{"name":"Department of Theoretical Physics, Atomic and Optics University of Valladolid Valladolid Spain"},{"name":"Instituto de Oftalmobiolog\u00eda Aplicada (IOBA) University of Valladolid Valladolid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4854-3592","authenticated-orcid":false,"given":"Ainhoa","family":"Molina\u2010Mart\u00edn","sequence":"additional","affiliation":[{"name":"Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy University of Alicante Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Bataille","sequence":"additional","affiliation":[{"name":"Visitrain S.L. Science Park of the University of Alicante Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1546-4807","authenticated-orcid":false,"given":"David P.","family":"Pi\u00f1ero","sequence":"additional","affiliation":[{"name":"Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy University of Alicante Alicante Spain"},{"name":"Visitrain S.L. Science Park of the University of Alicante Alicante Spain"},{"name":"Department of Ophthalmology Vithas Medimar International Hospital Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2017.1176"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.13094"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60272-4"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2016.01.006"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.12.104034"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.10.029"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13788"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.61.4.6"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000512396"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886\u2010023\u201002775\u2010x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13901"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2018.10.021"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2019.11.005"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11030542"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12292"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.13279"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2020.11.002"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2020.08.005"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2017.10.010"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000560"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886\u2010016\u20100355\u20105"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20160405-05"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3181940669"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.523835"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11206200"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12388"}],"container-title":["Ophthalmic and Physiological Optics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/opo.13402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T11:24:36Z","timestamp":1767785076000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/opo.13402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,3]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/opo.13402"],"URL":"https:\/\/doi.org\/10.1111\/opo.13402","archive":["Portico"],"relation":{},"ISSN":["0275-5408","1475-1313"],"issn-type":[{"value":"0275-5408","type":"print"},{"value":"1475-1313","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,3]]},"assertion":[{"value":"2024-06-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}