{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T13:57:39Z","timestamp":1784037459523,"version":"3.55.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870680"],"award-info":[{"award-number":["81870680"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQ22H120003"],"award-info":[{"award-number":["LQ22H120003"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The aim of this study was to investigate changes in the light\u2010adapted (LA) electroretinogram (ERG) associated with paediatric amblyopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A total of 220 eyes from 81 postoperative paediatric cataract patients and 29 healthy children were enrolled in four groups, namely controls, unilaterally amblyopic eyes, non\u2010amblyopic fellow eyes and bilaterally affected eyes. Differences in LA ERG variables (peak time and amplitude of a\u2010 and b\u2010waves and photopic negative response [PhNR]) were compared across groups, as well as their associations with visual acuity and changes in axial length.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The peak time of both the a\u2010wave (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and b\u2010wave (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), as well as the amplitude of the b\u2010wave (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and the PhNR (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04) differed significantly across groups. Compared to controls, affected eyes in both unilateral and bilateral groups showed significantly lower b\u2010wave amplitude and longer a\u2010 and b\u2010wave peak times (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.008, Bonferroni\u2010corrected). Additionally, fellow eyes in the unilateral group exhibited significantly longer b\u2010wave peak times (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008). For all eyes, poorer visual acuity was associated with a longer peak time for both the a\u2010 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and b\u2010waves (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003), as well as lower amplitudes of the b\u2010wave (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and PhNR (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Changes in LA ERG components suggest alteration of retinal physiology in deprivation amblyopia. Thus, the LA ERG may provide additional information to help understand the mechanisms underlying deprivation amblyopia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13430","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T08:55:29Z","timestamp":1733216129000},"page":"471-479","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Associations of light\u2010adapted electroretinogram in paediatric amblyopia"],"prefix":"10.1007","volume":"45","author":[{"given":"Bing","family":"Zhang","sequence":"first","affiliation":[{"name":"Eye Hospital and School of Ophthalmology and Optometry Wenzhou Medical University  Wenzhou China"},{"name":"National Clinical Research Centre for Ocular Diseases  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Wang","sequence":"additional","affiliation":[{"name":"Eye Hospital and School of Ophthalmology and Optometry Wenzhou Medical University  Wenzhou China"},{"name":"National Clinical Research Centre for Ocular Diseases  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yalan","family":"Wang","sequence":"additional","affiliation":[{"name":"Eye Hospital and School of Ophthalmology and Optometry Wenzhou Medical University  Wenzhou China"},{"name":"National Clinical Research Centre for Ocular Diseases  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Jiang","sequence":"additional","affiliation":[{"name":"Eye Hospital and School of Ophthalmology and Optometry Wenzhou Medical University  Wenzhou China"},{"name":"National Clinical Research Centre for Ocular Diseases  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4401-8053","authenticated-orcid":false,"given":"Yun\u2010e","family":"Zhao","sequence":"additional","affiliation":[{"name":"Eye 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