{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:17:26Z","timestamp":1787015846237,"version":"build-2736575974"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T00:00:00Z","timestamp":1743638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate the change in subfoveal choroidal thickness (SFChT) in bilateral anisomyopic children undergoing orthokeratology (ortho\u2010k) over 2\u2009years and the association with axial elongation (AE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>SFChT, axial length and refractive data from 26 bilateral anisomyopic subjects (aged 7\u201312\u2009years) who participated in a 2\u2010year prospective orthokeratology study were analysed using generalised estimating equations and linear mixed models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      SFChT in the more myopic eyes (MME) (at least 1.50 D more myopia than the fellow eye) became thicker (mean\u2009\u00b1\u2009standard deviation change, 25\u2009\u00b1\u200920\u2009\u03bcm) after 6\u2009months of ortho\u2010k lens wear (\n                      <jats:italic>p\u2009&lt;<\/jats:italic>\n                      \u20090.001) and remained stable thereafter (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2265\u20090.13), but no such change was observed in the less myopic eyes (LME) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2265\u20090.07). Combining data from both eyes, the baseline SFChT and SFChT change after 2\u2009years of ortho\u2010k treatment were associated with 2\u2010year AE [generalised estimating equation (accounting for the inclusion of both eyes): \u03b2\u2009=\u20090.002,\n                      <jats:italic>p\u2009=<\/jats:italic>\n                      \u20090.03 and \u03b2\u2009=\u2009\u22120.005,\n                      <jats:italic>p\u2009&lt;<\/jats:italic>\n                      \u20090.001, respectively].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>After 2\u2009years of ortho\u2010k treatment, the increase in the SFChT occurred exclusively in the MME. Considering both eyes, greater SFChT thickening was associated with less eye growth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13503","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T22:48:30Z","timestamp":1743806910000},"page":"1049-1055","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8215-2806","authenticated-orcid":false,"given":"Jianglan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5998-1320","authenticated-orcid":false,"given":"Stephen 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