{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:05:11Z","timestamp":1777334711633,"version":"3.51.4"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["EY022313"],"award-info":[{"award-number":["EY022313"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013400","name":"American Academy of Optometry Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013400","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare the longitudinal development of spherical equivalent refraction (SER) and ocular biometric components in the more hyperopic (MoreH) and less hyperopic (LessH) eyes of children with hyperopic anisometropia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective longitudinal study included 36 children aged 4 to &lt;13\u2009years with hyperopic anisometropia without strabismus. Based on a best\u2010corrected interocular visual acuity difference \u22650.20 logMAR, participants were classified as amblyopic (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200931) or non\u2010amblyopic (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u20095). SER was derived from cycloplegic refraction and anisometropia was defined as an interocular SER difference\u2009\u22651 D. Axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and keratometry (K1, K2) were obtained. Corneal curvature (CR) was calculated and the AL\/CR ratio determined. Mean follow\u2010up was 3.7\u2009\u00b1\u20091.4\u2009years, with 5.8\u2009\u00b1\u20092.4 visits per child. A linear mixed\u2010effects model estimated the rate of change for SER and the ocular components, comparing the MoreH and LessH eyes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline anisometropia was 2.66\u2009\u00b1\u20091.22 D. There were significant differences between the MoreH and LessH eyes for baseline AL, ACD and AL\/CR (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). SER change with age was slower for the MoreH than the LessH eyes (\u22120.11 vs. \u22120.31 D\/year,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The rates of change for AL (0.11 vs. 0.19\u2009mm\/year,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) and AL\/CR (0.01 vs. 0.02,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) also were slower for the MoreH eyes. Anisometropia increased with age in the amblyopic subgroup (0.08 D\/year) and decreased in the non\u2010amblyopic subgroup (\u22120.17\/D\/year;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In children with hyperopic anisometropia, axial elongation was slower in the MoreH than in the LessH eyes, particularly in those with amblyopia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13541","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T11:03:33Z","timestamp":1749812613000},"page":"1423-1434","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Longitudinal development of ocular biometric components and refractive error in children with hyperopic anisometropia"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9073-2349","authenticated-orcid":false,"given":"Jingyun","family":"Wang","sequence":"first","affiliation":[{"name":"State University of New York College of Optometry  New York City New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reed M.","family":"Jost","sequence":"additional","affiliation":[{"name":"Retina Foundation of the Southwest  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brooke A.","family":"Koritala","sequence":"additional","affiliation":[{"name":"Retina Foundation of the Southwest  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen E.","family":"Birch","sequence":"additional","affiliation":[{"name":"Retina Foundation of the Southwest  Dallas Texas USA"},{"name":"Department of Ophthalmology UT Southwestern Medical Center  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,13]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.11.1625"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000001296"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2015.0471"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2020.0412"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3181c95a24"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.62.5.3"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-25967"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1076\/stra.11.2.71.15104"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.80.10.860"},{"key":"e_1_2_12_11_1","first-page":"41","article-title":"Emmetropisation and accommodation in hypermetropic children before they show signs of squint\u2014a preliminary analysis","volume":"253","author":"Ingram RM","year":"1994","journal-title":"Bull Soc Belge Ophtalmol"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-316406"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.04.061"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000223"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-18454"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(75)90212-3"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00159077"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2012.02.035"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2010.129"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0906"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2003.00062.x"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-1313.2011.00850.x"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0203584"},{"key":"e_1_2_12_24_1","unstructured":"AAO.American Academy of Ophthalmology Preferred Practice Patterns for Amblyopia.2022. Available from:https:\/\/www.aao.org\/education\/preferred\u2010practice\u2010pattern\/amblyopia\u2010ppp\u20102022. Accessed 9 June 2025."},{"key":"e_1_2_12_25_1","unstructured":"AAO.American Academy of Ophthalmology Preferred Practice Patterns for Pediatric Eye Evaluations.2022. Available from:https:\/\/www.aao.org\/education\/preferred\u2010practice\u2010pattern\/pediatric\u2010eye\u2010evaluations\u2010ppp\u20102022. Accessed 9 June 2025."},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199409000-00005"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01825-1"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.9.1345"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2007.08.014"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2021.01.003"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199706000-00019"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-1324"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-200303000-00012"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12814"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-198307000-00001"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000001970"},{"key":"e_1_2_12_37_1","article-title":"Inter\u2010eye differences in accommodation in anisometropic children with and without amblyopia","volume":"44","author":"Felius J","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-14948"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4969"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo-2021-321005"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2024.07.002"},{"key":"e_1_2_12_42_1","first-page":"1408","article-title":"Height and its relationship to refraction and biometry parameters in Singapore Chinese children","volume":"43","author":"Saw SM","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_12_43_1","first-page":"314","article-title":"Baseline refractive and ocular component measures of children enrolled in the correction of myopia evaluation trial (COMET)","volume":"43","author":"Gwiazda J","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12457"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2011.01.157"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2013.05.001"},{"key":"e_1_2_12_47_1","first-page":"987","article-title":"The association between anisometropia, amblyopia and binocularity in the absence of strabismus","volume":"97","author":"Weakley DR","year":"1999","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.13468"}],"container-title":["Ophthalmic and Physiological Optics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/opo.13541","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T11:24:35Z","timestamp":1767785075000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/opo.13541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,13]]},"references-count":47,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/opo.13541"],"URL":"https:\/\/doi.org\/10.1111\/opo.13541","archive":["Portico"],"relation":{},"ISSN":["0275-5408","1475-1313"],"issn-type":[{"value":"0275-5408","type":"print"},{"value":"1475-1313","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,13]]},"assertion":[{"value":"2025-03-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}