{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:36:07Z","timestamp":1783038967200,"version":"3.54.6"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the progression of myopia as assessed by changes in axial length (AL) and spherical equivalent (SE) in Caucasian children wearing extended depth of focus soft contact lenses (CL) compared with distance single\u2010vision spectacles after 3\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 96 progressing (at least \u22120.75 D increase in the previous 12\u2009months) myopic children (aged 6\u201313\u2009years) with SE ranging from \u22120.75 to \u221210.00 D were recruited. Forty\u2010five children were fitted with CL (MYLO), whereas 51 wore spectacles. Cycloplegic refraction was measured with an auto\u2010refractometer and AL with the Zeiss IOLMaster\u2010700 at 6\u2010month intervals. Subjective responses of CL wear were determined using a questionnaire on a scale of 1 (very poor) to 10 (excellent). High\u2010contrast visual acuity (HCVA) was also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 43 and 41 children achieved 3\u2009years of wear with CL and spectacles, respectively. Mean change in SE and AL was \u22120.90\u2009\u00b1\u20090.36 D and 0.55\u2009\u00b1\u20090.04\u2009mm in the CL group and \u22121.64\u2009\u00b1\u20090.26 D and 0.97\u2009\u00b1\u20090.03\u2009mm in the spectacle group, respectively (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The cumulative absolute reduction in axial elongation was 0.42\u2009mm. The difference in SE change was 0.74 D. While 90% of the children wearing CL had an AL increase of \u22640.60\u2009mm, 96% of the spectacle group increased by at least 0.91\u2009mm. Indeed, 50% of the CL group showed myopia progression of at least 0.75 D, whereas all the spectacle group progressed by at least 0.75 D. Subjective responses indicated a mean value \u22659. There was a reduction in HCVA of half a logMAR line with CL compared to spectacles (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Three years of wear with MYLO CL resulted in clinically significant slower myopia progression compared to the SV spectacle group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13549","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T08:11:40Z","timestamp":1751271100000},"page":"1512-1524","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Three\u2010year myopia management efficacy of extended depth of focus soft contact lenses (\n                    <scp>MYLO<\/scp>\n                    ) in Caucasian children"],"prefix":"10.1007","volume":"45","author":[{"given":"Sergio","family":"D\u00edaz\u2010G\u00f3mez","sequence":"first","affiliation":[{"name":"Faculty of Optics and Optometry Complutense University of Madrid  Madrid Spain"},{"name":"Miranza Centro Oftalmol\u00f3gico Integral (COI)  Bilbao Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5537-6193","authenticated-orcid":false,"given":"Padmaja","family":"Sankaridurg","sequence":"additional","affiliation":[{"name":"School of Optometry and Vision Science University of New South Wales  Sydney New\u00a0South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 A.","family":"L\u00f3pez\u2010Garrido","sequence":"additional","affiliation":[{"name":"Miranza Centro Oftalmol\u00f3gico Integral (COI)  Bilbao Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Burgos\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Mark'ennovy  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2795-1802","authenticated-orcid":false,"given":"Jes\u00fas","family":"Carballo\u2010\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Faculty of Optics and Optometry Complutense University of Madrid  Madrid 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