{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T04:31:11Z","timestamp":1791433871915,"version":"4.3.3"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To assess second\u2010year myopia progression in children after a 1\u2010year randomised controlled trial of individualised ocular refraction customisation (IORC) spectacle lenses, customised to each eye's peripheral refraction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 161 children were randomised to wear IORC lenses with high (+4.50 D, IORC\u2010H), medium (+3.50 D, IORC\u2010M) or low (+2.50 D, IORC\u2010L) myopic defocus or single\u2010vision lenses (SV). In year 2, all children received IORC\u2010H, forming the IORC\u2010H1\/H2\/H3\/H4 groups, respectively. An external SV (eSV,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200942) group was matched to year 2 baseline parameters. Spherical equivalent refraction (SER) and axial length (AL) were measured every 6\u2009months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with the eSV group (12\u2010month mean [SD] changes: SER \u22120.56 [0.44] D, AL 0.32 [0.16] mm), all IORC\u2010H intervention groups demonstrated slower progression in year 2 (IORC\u2010H1: \u22120.17 [0.37] D, 0.19 [0.14] mm; IORC\u2010H2: \u22120.25 [0.41] D, 0.17 [0.16] mm; IORC\u2010H3: \u22120.24 [0.36] D, 0.17 [0.14] mm; IORC\u2010H4: \u22120.22 [0.40] D, 0.14 [0.17] mm;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), with no intergroup differences (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Compared with the SV\/eSV group, the IORC\u2010H1 group presented 2\u2010year reductions of 0.84 D and 0.38\u2009mm in the SER and AL, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and exhibited minimal progression during the initial 0\u20136\u2009months (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), followed by constant progression over three subsequent 6\u2010month intervals (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Switching to IORC\u2010H in year 2 significantly reduced myopia progression and axial elongation. Maximal control efficacy occurred in the first 6\u2009months, with sustained clinically meaningful effects thereafter.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.70002","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T13:20:52Z","timestamp":1754918452000},"page":"1882-1893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Myopia control efficacy of individualised ocular refraction customisation spectacle lenses: A 2\u2010year follow\u2010up study"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9740-951X","authenticated-orcid":false,"given":"Ji","family":"Kou","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Optometry and Vision Sciences, West China Hospital Sichuan University  Chengdu 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