{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:15:36Z","timestamp":1788437736773,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,11,27]],"date-time":"2014-11-27T00:00:00Z","timestamp":1417046400000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:p>The <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content><jats:sub>1<\/jats:sub> lateral mass screw technique is widely used for atlantoaxial fixation. However, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content><jats:sub>2<\/jats:sub> nerve dysfunction may occur as a complication of this procedure, compromising the quality of life of affected patients. This is a review of the topic of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content><jats:sub>2<\/jats:sub> nerve dysfunction associated with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content><jats:sub>1<\/jats:sub> lateral mass screw fixation and related research developments. The C<jats:sub>2<\/jats:sub> nerve root is located in the space bordered superiorly by the posterior arch of C<jats:sub>1<\/jats:sub>, inferiorly by the C<jats:sub>2<\/jats:sub> lamina, anteriorly by the lateral atlantoaxial joint capsule, and posteriorly by the anterior edge of the ligamentum flavum. Some surgeons suggest cutting the C<jats:sub>2<\/jats:sub> nerve root during C<jats:sub>1<\/jats:sub> lateral mass screw placement, whereas others prefer to preserve it. The incidence, clinical manifestations, causes, management, and prevention of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content><jats:sub>2<\/jats:sub> nerve dysfunction associated with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content><jats:sup>1<\/jats:sup> lateral mass screw fixation are reviewed. Sacrifice of the C<jats:sub>2<\/jats:sub> nerve root carries a high risk of postoperative numbness, whereas postoperative nerve dysfunction can occur when it has been preserved. Many surgeons have been working hard on minimizing the risk of postoperative C<jats:sub>2<\/jats:sub> nerve dysfunction associated with C<jats:sub>1<\/jats:sub> lateral mass screw fixation.<\/jats:p>","DOI":"10.1111\/os.12136","type":"journal-article","created":{"date-parts":[[2014,11,28]],"date-time":"2014-11-28T15:27:40Z","timestamp":1417188460000},"page":"269-273","source":"Crossref","is-referenced-by-count":26,"title":["<scp>C<sub>2<\/sub><\/scp> Nerve Dysfunction Associated with <scp>C<sub>1<\/sub><\/scp> Lateral Mass Screw Fixation"],"prefix":"10.1111","volume":"6","author":[{"given":"Da\u2010geng","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Spine Surgery Honghui Hospital, Xi'an Jiaotong University Health Science Center  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding\u2010jun","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery Honghui Hospital, Xi'an Jiaotong University Health 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