{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T17:54:24Z","timestamp":1769190864616,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T00:00:00Z","timestamp":1440547200000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the characteristics of inter body fusion after using an established poly (<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010lactic acid) (<jats:styled-content style=\"fixed-case\">PDLLA<\/jats:styled-content>) cage, a titanium cage or autologous tricortical iliac crest graft in a goat cervical spine model <jats:italic>in vivo<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010four goats were assigned to three groups: <jats:styled-content style=\"fixed-case\">PDLLA<\/jats:styled-content> cage group (<jats:italic>n<\/jats:italic> = 8), titanium alloy cage group (<jats:italic>n<\/jats:italic> = 8) and autologous iliac bone group (<jats:italic>n<\/jats:italic> = 8), and underwent <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content><jats:sub>3\u20104<\/jats:sub> discectomy and fusion with the allocated procedure. Radiography was performed pre\u2010 and post\u2010operatively and after 1, 2, 4, 8 and 12 weeks and disc space height (<jats:styled-content style=\"fixed-case\">DSH<\/jats:styled-content>), intervertebral angle (<jats:styled-content style=\"fixed-case\">IVA<\/jats:styled-content>), and lordosis angle (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) measured at these time points. After 12 weeks, the goats were killed and fusion sites removed. Biomechanical testing was performed in flexion, extension, axial rotation, and lateral bending to determine the stiffness and range of motion (ROM). All specimens were also assessed histomorphologically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">IVA<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">PDLLA<\/jats:styled-content> cage four weeks postoperatively and <jats:styled-content style=\"fixed-case\">DSH<\/jats:styled-content> eight and twelve weeks postoperatively were significantly greater than that of autologous iliac bone graft (<jats:italic>P<\/jats:italic> &lt; 0.05). The <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> values did not differ significantly between groups. The stiffness of both types of cages for axial rotation and lateral bending, and ROM for every movement, were significantly greater than that of the autologous iliac bone graft group (<jats:italic>P<\/jats:italic> &lt; 0.05). <jats:styled-content style=\"fixed-case\">PDLLA<\/jats:styled-content> and titanium cages did not differ significantly (<jats:italic>P<\/jats:italic> &gt; 0.05). Radiographic and histomorphological assessment showed better fusion in the cage than the autologous bone groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">PDLLA<\/jats:styled-content> cage can provide good intervertebral distract ability and enough biomechanical stability for cervical fusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.12192","type":"journal-article","created":{"date-parts":[[2015,8,27]],"date-time":"2015-08-27T03:59:40Z","timestamp":1440647980000},"page":"266-272","source":"Crossref","is-referenced-by-count":6,"title":["Reconstruction of Segmental Stability of Goat Cervical Spine with Poly (<scp>D, L<\/scp>\u2010lactic acid) Cage"],"prefix":"10.1111","volume":"7","author":[{"given":"Xiao\u2010hui","family":"Li","sequence":"first","affiliation":[{"name":"Department of Orthopaedics Tianjin Hospital  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue\u2010ming","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,8,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-195840030-00009"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1958.15.6.0602"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-012-1092-y"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.11.1017"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-197510000-00016"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000507"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2014.06.011"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181e8e4a3"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0b013e3181b63da6"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-007-0337-7"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-921404"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00024720-200312000-00005"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200208150-00003"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-14-244"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000134565.17078.4C"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000176330.21332.e4"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002517-199412000-00004"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198908000-00019"},{"key":"e_1_2_5_20_1","first-page":"37","article-title":"Comparison of outcomes and safety of using hydroxyapatite granules as a substitute for autograft in cervical cages for anterior cervical discectomy and interbody fusion","volume":"2","author":"Mashhadinezhad H","year":"2014","journal-title":"Arch Bone Jt Surg"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.4184\/asj.2013.7.1.34"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/09593985.2012.731627"}],"container-title":["Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fos.12192","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.12192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T19:37:57Z","timestamp":1696275477000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/os.12192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/os.12192"],"URL":"https:\/\/doi.org\/10.1111\/os.12192","archive":["Portico"],"relation":{},"ISSN":["1757-7853","1757-7861"],"issn-type":[{"value":"1757-7853","type":"print"},{"value":"1757-7861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8]]}}}