{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:42:33Z","timestamp":1790095353242,"version":"4.0.1"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T00:00:00Z","timestamp":1574294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007162","name":"Guangdong Science and Technology Department","doi-asserted-by":"publisher","award":["2016A020215137"],"award-info":[{"award-number":["2016A020215137"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2016A030313641"],"award-info":[{"award-number":["2016A030313641"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010883","name":"Traditional Chinese Medicine Bureau of Guangdong Province","doi-asserted-by":"publisher","award":["20191098"],"award-info":[{"award-number":["20191098"]}],"id":[{"id":"10.13039\/501100010883","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Treatment for osteoporotic vertebral fracture (OVF) with cord compression is challenging and it usually requires surgical interventions to decompress nerves and restore spinal sequences. To describe a novel surgical strategy for treating OVFs with cord compression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a single\u2010center retrospective analysis. The inclusion criteria were Frankel grade C\u2010E, single level T<jats:sub>10<\/jats:sub>\u2010L<jats:sub>2<\/jats:sub>. Between January 2008 and December 2016, a total of 56 OVF patients (47 females and nine males, with an average age of 72\u2009years (66\u201388\u2009years), comprising of eight grade C, 23 grade D, and 25 grade E patients) were enrolled. The treatment algorithm included preoperative evaluation by MRI, extension CT, and radiography to classify the OVFs as type 1.1 (reducible, stable; <jats:italic>n\u2009=<\/jats:italic>\u200913), type1.2 (reducible, unstable; <jats:italic>n\u2009=<\/jats:italic>\u200916), type 2 (irreducible; <jats:italic>n\u2009=<\/jats:italic>\u200919) or type 2M (modifier; <jats:italic>n\u2009=<\/jats:italic>\u20098). Vertebroplasty (VP)\/kyphoplasty (KP) was applied in type 1.1. VP\/KP with posterior fixation and posterolateral fusion was applied in type 1.2. And additional laminectomy\/osteotomy was used in type 2, except in a modifier group (2M) where same procedure as applied for type 1.2 was used. VAS, ODI, Cobb angle, Frankel functional grade, and complications were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirteen cases were classified as type 1.1, 16 cases as type 1.2, 19 cases as type 2, and eight cases as type 2M. The follow\u2010up period was 38.9 months (range, 24\u2013108 months). All patients were followed\u2010up in at least 24 months, in which time four patients died, two patients were lost at the last follow\u2010up, and 50 patients completed the full study. The total VAS and ODI improved from 8 (7, 9) and 75.5% (67.2%, 80.0%) preoperatively to 2 (1, 3) and 31% (24.0%, 37.0%) on conclusion, respectively (<jats:italic>P<\/jats:italic> &lt;\u20090.01). The local kyphotic angle was corrected from 22.3\u00b0 (17.1\u00b0, 33. 8\u00b0) preoperatively to 10.4\u00b0 (6.4\u00b0, 15.3\u00b0) on conclusion (<jats:italic>P<\/jats:italic> &lt;\u20090.01). Twenty\u2010three patients had achieved neurological recovery on conclusion (42E, 8D, <jats:italic>P<\/jats:italic> &lt;\u20090.01). Asymptotic cement leakage was observed in 17\/56 cases (30.4%), 6\/56 in the affected vertebra (10.7%), and 24\/330 in the screw trajectory (7.3%). At 2\u2009years postoperatively, 11 new VFs had occurred in nine patients (16.1%), including VFs in nine adjacent segments that all occurred within 1 year after surgery. No cement migration or implant failure was noted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The novel surgical strategy for treating OVFs with cord compression consists of the most tailored and least invasive treatment for each patient. The positive mid\u2010 and long\u2010term clinical and radiological outcomes observed could represent a step forward in devising the proposed algorithm.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.12558","type":"journal-article","created":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T10:45:56Z","timestamp":1574333156000},"page":"1082-1092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Novel Surgical Strategy for Treating Osteoporotic Vertebral Fractures with Cord Compression"],"prefix":"10.1111","volume":"11","author":[{"given":"Dan\u2010qing","family":"Guo","sequence":"first","affiliation":[{"name":"The 1st Institute of Clinical Medicine, Guangzhou University of Chinese Medicine  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Yu","sequence":"additional","affiliation":[{"name":"Spine Surgery Department Foshan Hospital of Chinese Medicine  Foshan 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