{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:20:26Z","timestamp":1791973226873,"version":"4.3.4"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T00:00:00Z","timestamp":1606003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2020,12]]},"abstract":"\n Objective<\/jats:title>\n To investigate the correlation between magnetic resonance imaging (MRI) lamellated hyperintense synovitis and periprosthetic infection of hip arthroplasty and estimate its value in the diagnosis of infection after hip replacement.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A retrospective analysis of 50 patients who underwent MRI from January 2016 to June 2019 after hip replacement was performed. The MRI scanning was performed with a 1.5T clinical imaging unit using SEMAC protocols. A total of 25 patients (cohort 1) showed infected total hip arthroplasty, and 25 patients had non\u2010infected arthroplasty as controls (cohort 2). Two musculoskeletal radiologists, blinded to the clinical diagnosis, reviewed all the images for the presence of lamellated hyperintense synovitis independently. The cases were rereviewed by each reader after 2\u2009weeks. The sensitivity, specificity, positive predictive value, and negative predictive value were calculated using the first reads. The Kappa statistic was used to assess inter\u2010observer and intra\u2010observer reliability.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The incidence of lamellated hyperintense synovitis was 76%\u201388% in the experimental group and 8%\u201316% in the control group. The sensitivity of lamellated hyperintense synovitis for infection was 0.80\u20130.88 (95% confidence interval [CI]:0.59\u2009\u2013\u20090.97), the specificity was 0.84~0.92 (95% CI: 0.64\u2009\u2009\u20130.99), the positive predictive value 0.83\u20130.92 (95% CI: 0.67\u2009\u2013\u20090.98), the negative predictive value 0.81 \u2013 0.88 (95% CI: 0.65\u2009\u2013\u20090.96). The agreement between two readers was substantial (Kappa = 0.76, 95% CI: 0.58\u2009\u2013\u20090.94,\n P<\/jats:italic>\n <\u20090.05). There were moderate inter\u2013observer agreements for both readers, reader 1 (Kappa = 0.48, 95%CI: 0.23 \u2013 0.72,\n P<\/jats:italic>\n <\u20090.05) and reader 2 (Kappa = 0.44\uff0c95% CI: 0.19\u2009\u2013\u20090.69,\n P<\/jats:italic>\n <\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n In this cohort, the presence of lamellated hyperintense synovitis in the MRI of hip arthroplasty showed high sensitivity and specificity for infection. This sign had substantial intra\u2010observer reliability and moderate inter\u2010observer reliability in the classification of the synovial pattern.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/os.12789","type":"journal-article","created":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T01:37:34Z","timestamp":1606095454000},"page":"1941-1946","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Diagnostic Value of\n MRI<\/scp>\n Lamellated Hyperintense Synovitis in Periprosthetic Infection of Hip"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5851-0247","authenticated-orcid":false,"given":"Zongyan","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Orthopedics People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Orthopedics People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhipeng","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Orthopedics People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Qiang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyuan","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2084-963X","authenticated-orcid":false,"given":"Jincheng","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Orthopedics People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"j4651","DOI":"10.1136\/bmj.j4651","article-title":"Choice of implant combinations in total hip replacement: systematic review 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