{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T04:10:07Z","timestamp":1785557407296,"version":"3.56.0"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T00:00:00Z","timestamp":1622592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2020KH011"],"award-info":[{"award-number":["ZR2020KH011"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2020MH362"],"award-info":[{"award-number":["ZR2020MH362"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81473709"],"award-info":[{"award-number":["81473709"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore the safety and efficacy of percutaneous pedicle screw fixation combined with vertebroplasty for the treatment of stage III K\u00fcmmell disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The clinical data and follow\u2010up results of 22 patients with K\u00fcmmell disease who were admitted to our department from 2014 to 2018 were analyzed. There were 14 females and eight males, and the Age range was 58\u201381\u2009years. All patients were followed up for 24\u2009months. The treatment method was percutaneous pedicle screw fixation combined with vertebroplasty. The patient general information such as age, gender, bedrest time and location of fracture vertebrae were recorded. The clinical symptoms and imaging data of visual analogue scale (VAS), bone cement leakage, Oswestry Disability Index (ODI), Cobb angle, anterior, middle and posterior height of the diseased vertebral body, and complications were recorded before operation and during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For patients enrolled, no bone cement leakage was observed during the operation; no patients developed infections after operation. The operation was safe and resulted in a short bedrest time. The VAS score and ODI index at 3 and 24\u2009months postoperative (2.86 \u00b1\u20090.83, 31.68% \u00b1\u20096.21%; 3.0 \u00b1\u20090.82, 32.78% \u00b1\u20096.05%) were significantly lower than that recoded preoperatively (7.59 \u00b1\u20090.59, 71.5% \u00b1\u20098.84%) (<jats:italic>P<\/jats:italic> &lt;\u20090.05). Additionally, there was no significant difference between the records at 3 and 24 months after operation (<jats:italic>P<\/jats:italic> &gt;\u20090.05). Imaging data showed that the bone cement and screws were in good position and did not move during postoperative and follow\u2010up. The anterior, middle and posterior height of the diseased vertebral body measured 2\u2009days after surgery (23.46 \u00b1\u20094.72, 23.12 \u00b1\u20093.05, 25.81 \u00b1\u20092.22) and at last follow\u2010up (20.83 \u00b1\u20094.48, 21.78 \u00b1\u20092.74, 24.74 \u00b1\u20091.93) were higher than that recorded preoperatively (13.08 \u00b1\u20094.49, 12.93 \u00b1\u20093.53, 19.32 \u00b1\u20092.73) (<jats:italic>P<\/jats:italic> &lt;\u20090.05), and the Cobb angle measured 2\u2009days and 24\u2009months after operation (9.57 \u00b1\u20094.63, 10.68 \u00b1\u20093.97) were lower than that recorded preoperatively (28.24 \u00b1\u20098.95) (<jats:italic>P<\/jats:italic> &lt;\u20090.05), and no significant difference was found between the values recorded at 2\u2009days and 24\u2009months after operation (<jats:italic>P<\/jats:italic> &gt;\u20090.05). Follow\u2010up for 24\u2009months, there was no re\u2010fracture of the diseased vertebrae and internal fixation loosening, but two cases of adjacent vertebral refracture complications occurred, and the effect was good after PVP treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Short\u2010segment percutaneous pedicle screw fixation combined with vertebroplasty in the treatment of stage III K\u00fcmmel disease can effectively restore the height of the diseased vertebrae, kyphosis correction, reduce trauma, prevent the diseased vertebral body from collapsing again, and effectively improves clinical symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.12935","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T12:10:33Z","timestamp":1622635833000},"page":"1505-1512","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Clinical Observations of <scp>K\u00fcmmell<\/scp> Disease Treatment Through Percutaneous Fixation Combined with Vertebroplasty"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5741-3832","authenticated-orcid":false,"given":"Dong\u2010Hao","family":"Gan","sequence":"first","affiliation":[{"name":"First College of Clinical Medicine Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng\u2010Ze","family":"Fang","sequence":"additional","affiliation":[{"name":"College of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai\u2010Peng","family":"Xue","sequence":"additional","affiliation":[{"name":"First College of Clinical Medicine Shandong University of Traditional Chinese Medicine  Jinan China"},{"name":"Department of Orthopedics Affilited Hospital of Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo\u2010Qing","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Affilited Hospital of Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nian\u2010Hu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Affilited Hospital of Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi\u2010Chao","family":"Li","sequence":"additional","affiliation":[{"name":"First College of Clinical Medicine Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhan\u2010Wang","family":"Xu","sequence":"additional","affiliation":[{"name":"First College of Clinical Medicine Shandong University of Traditional Chinese Medicine  Jinan China"},{"name":"Department of Orthopedics Affilited Hospital of Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S131023"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32112-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/os.12609"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-011-1789-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.141.2.7291557"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.06.106"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-007-0684-0"},{"key":"e_1_2_6_9_1","first-page":"1634","article-title":"Vacuum clefts of the vertebral bodies","volume":"26","author":"Mirovsky Y","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(51)90206-1"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/os.12730"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323001204000202"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-006-0094-z"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000076824.61074.06"},{"key":"e_1_2_6_15_1","first-page":"3617","article-title":"Percutaneous kyphoplasty treatment evaluation for patients with K\u00fcmmell disease based on a two\u2010year follow\u2010up","volume":"16","author":"Xia YH","year":"2018","journal-title":"Exp Ther Med"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2016.03.035"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181657f31"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000538"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0000000000000259"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurad.2013.07.004"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-3768-6"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00302145"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-018-3832-z"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001467"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3878063"},{"key":"e_1_2_6_26_1","first-page":"E1021","article-title":"Percutaneous kyphoplasty for Kummell disease with severe spinal canal stenosis","volume":"18","author":"Chen GD","year":"2015","journal-title":"Pain Physician"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.905875"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012183"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2015.03.016"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/0954411915612494"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.905804"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.3171\/2015.10.SPINE15511"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.3171\/2015.10.SPINE141275"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-1383(15)30020-6"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-016-3129-z"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-016-4908-3"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001814"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-3021-x"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2015\/18\/E1101"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200107150-00009"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2848-5"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31828cf15b"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-011-2099-5"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2011.01297.x"}],"container-title":["Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.12935","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/os.12935","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.12935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T05:08:14Z","timestamp":1693285694000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/os.12935"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,2]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/os.12935"],"URL":"https:\/\/doi.org\/10.1111\/os.12935","archive":["Portico"],"relation":{},"ISSN":["1757-7853","1757-7861"],"issn-type":[{"value":"1757-7853","type":"print"},{"value":"1757-7861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,2]]},"assertion":[{"value":"2020-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}