{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:13:42Z","timestamp":1792512822414,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,5]],"date-time":"2021-12-05T00:00:00Z","timestamp":1638662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2022,1]]},"abstract":"\n Objectives<\/jats:title>\n The objective is to determine whether the preoperative duration of symptoms can affect the clinical and functional outcomes after microdiscectomy.<\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n This study is a single blind randomized controlled trial with level 1 evidence. From 3 January 2016 to 15 February 2017, 122 adult patients with symptomatic lumbar disc herniation were divided randomly by computer system into three groups were treated by microdiscectomy at 6\u2009weeks, 3 months and 6 months from onset of symptoms respectively. Ninety\u2010seven patients, age (19\u201347) years, 42 males and 55 females, were analyzed at the end of this study with 3\u2009years of follow up. Primary outcome measures are Oswestry Disability Index (ODI), Roland\u2010Morris Questionnaire (RMQ) and Visual Analogue Scale (VAS) for back pain and leg pain. Secondary outcome measures are post\u2010operative complications, length of hospital stay and time of return to daily activities.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There was significant difference in VAS for back pain among study groups (\n P<\/jats:italic>\n \u00a0=\u00a00.002) at 2\u2009weeks). There were significant differences in VAS for leg pain among study groups (\n P<\/jats:italic>\n <\u20090.001) at 2\u2009weeks and at 3\u2009months (\n P<\/jats:italic>\n \u00a0=\u00a00.003). There was significant difference in ODI among study groups at 2\u2009weeks, 3, 6 months, 1, 2 and 3\u2009years (\n P<\/jats:italic>\n \u00a0=\u00a00.037 at 2\u2009weeks and\n P<\/jats:italic>\n <\u20090.001 at other periods of assessments) and we found that the mean of ODI in group 6\u2009weeks was better than group 3 months and this was better than group 6 months in all periods of assessment. Group 6\u2009weeks was better than group 3 months and this was better than group 6 months in postoperative improvements regarding RMQ with significant difference at 2\u2009weeks postoperatively (\n P<\/jats:italic>\n <\u20090.001) and at 3 months postoperatively (\n P<\/jats:italic>\n <\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Duration of preoperative symptoms, in patients with lumbar disc herniation, can affect the clinical and functional outcomes after lumbar microdiscectomy as the shorter duration of symptoms resulted in better postoperative clinical and functional outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/os.13114","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T02:27:42Z","timestamp":1638757662000},"page":"157-168","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of Duration of Symptoms on the Clinical and Functional Outcomes of Lumbar Microdiscectomy: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6521-1840","authenticated-orcid":false,"given":"Sherwan A","family":"Hamawandi","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery College of Medicine, Hawler Medical University Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Injam I","family":"Sulaiman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, College of Medicine Hawler Medical University Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali M","family":"Abdulhameed","sequence":"additional","affiliation":[{"name":"Orthopedic Surgeon, Erbil Teaching Hospital Erbil Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199301000-00005"},{"key":"e_1_2_8_3_1","first-page":"116","article-title":"Etude comparative de la chirurgie discale avec et sans microscope. Analyse prospective de 80 cas [Comparative study of disk surgery with or without microscopy. A prospective study of 80 cases]","volume":"40","author":"Lagarrigue J","year":"1994","journal-title":"Neurochirurgie"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199805150-00019"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2005.2.3.0271"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/2015.7.FOCUS15281"},{"key":"e_1_2_8_7_1","first-page":"E863","article-title":"Comparison of 7 surgical interventions for lumbar disc herniation: a network meta\u2010analysis","volume":"20","author":"Feng F","year":"2017","journal-title":"Pain Physician"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-020-03396-x"},{"key":"e_1_2_8_9_1","first-page":"131","article-title":"Duration of leg pain as a predictor of outcome after surgery for lumbar disc herniation: a prospective cohort study with 1\u2010year follow up","volume":"92","author":"Nygaard OP","year":"2000","journal-title":"J Neurosurg"},{"key":"e_1_2_8_10_1","first-page":"317","article-title":"Outcome evaluation of the operative management of lumbar disc herniation causing sciatica","volume":"100","author":"Fisher C","year":"2004","journal-title":"J Neurosurg"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.86B4.14419"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/565189"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3126\/kumj.v13i4.16833"},{"key":"e_1_2_8_14_1","first-page":"RC09","article-title":"Functional outcome of lumbar discectomy by fenestration technique in lumbar disc prolapse\u2014return to work and relief of pain","volume":"10","author":"Wankhade UG","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2015.12.097"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-018-2240-2"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-017-2043-4"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-018-2359-8"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0000000000000711"},{"key":"e_1_2_8_20_1","volume-title":"Biostatistics; a foundation for analysis in the health sciences","author":"Daniel W","year":"2013"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200011150-00017"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/76.4.359"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2702.2005.01121.x"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjtee.2016.12.002"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.4076\/1757-1626-2-8584"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/2192568217745512"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-017-9450-3"}],"container-title":["Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.13114","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/os.13114","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.13114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:28:15Z","timestamp":1693182495000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/os.13114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,5]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1111\/os.13114"],"URL":"https:\/\/doi.org\/10.1111\/os.13114","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-78739\/v1","asserted-by":"object"}]},"ISSN":["1757-7853","1757-7861"],"issn-type":[{"value":"1757-7853","type":"print"},{"value":"1757-7861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,5]]},"assertion":[{"value":"2020-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}