{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T01:19:02Z","timestamp":1783646342924,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T00:00:00Z","timestamp":1643500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004835","name":"Zhejiang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004835","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To tackle the challengeable dilemma of delayed femoral fracture, a technique of fixator\u2010assisted closed reduction and intramedullary nailing at one stage was introduced herein and its clinical results were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was conducted on delayed femoral shaft fracture between February 2008 and January 2017. The multiple injured patients aged from 18 to 60\u2009years with delayed femoral fracture was included. All patients were treated by one\u2010stage internal fixation technique and followed up for more than 1\u2009year. Outcome measures including the operation time, intraoperative blood loss and limb alignment, healing time of fracture, visual analog scale (VAS), and range of knee motion were recorded and evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 13 patients (16 sides) with a mean injury severity score (ISS) of 32.77\u2009\u00b1\u20099.98 (range, 19 to 52) participated in the investigation. The median length of time\u2010after\u2010fracture was 38\u2009days (range, 21 to 110\u2009days). The average shortening distance of the fracture ends was 35.48\u2009\u00b1\u200919.24\u2009mm (range, 10.00 to 79.00\u2009mm). The average surgery time was 192.19\u2009\u00b1\u200929.38 min for unilateral femoral fracture, with blood loss of 587.50\u2009\u00b1\u2009232.02 ml. The postoperative discrepancy of lower limb was 3.87\u2009\u00b1\u20092.52\u2009mm. No patient had vascular and neurologic complications due to the lengthening. All fractures healed successfully with a mean time of 2.98\u2009\u00b1\u20090.57\u00a0months. The mean VAS and maximal knee flexion were 1.63\u2009\u00b1\u20091.09 and 131.25\u00b0\u2009\u00b1\u20095.32\u00b0 at final follow\u2010up, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings indicated that fixator\u2010assisted closed reduction and intramedullary nailing at one stage is an effective treatment for delayed femoral fracture with satisfactory functional recovery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13206","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T06:00:22Z","timestamp":1643608822000},"page":"501-512","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["One\u2010Stage Closed Intramedullary Nailing for Delayed Femoral Fracture in Multiple Injured Patients"],"prefix":"10.1111","volume":"14","author":[{"given":"Ruijian","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery 2nd Affiliated Hospital, School of Medicine, Zhejiang University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of surgery 2nd Affiliated Hospital, School of Medicine, Zhejiang University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiying","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery 2nd Affiliated Hospital, School of Medicine, Zhejiang University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery 2nd Affiliated Hospital, School of Medicine, Zhejiang University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shurong","family":"Dong","sequence":"additional","affiliation":[{"name":"Institute of Microelectronics and Nanoelectronics Key Lab. of Advanced Micro\/Nano Electronics Devices &amp; Smart Systems of Zhejiang, College of Information Science &amp; Electronic Engineering, Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2683-3353","authenticated-orcid":false,"given":"Gang","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery 2nd Affiliated Hospital, School of Medicine, Zhejiang University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcot.2013.05.003"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(17)30222-X"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.5455\/medarh.2015.69.260-264"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2019.03.016"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/230949901001800110"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2014.164"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-1383(95)00091-M"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200006000-00004"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2008.06.028"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-013-3293-z"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-11-133"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200905000-00004"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.5455\/aim.2016.24.261-265"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0010.4646"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ta.0000197431.05396.27"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-013-3292-0"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199403000-00008"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.5455\/aim.2016.24.394-396"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.5455\/medarh.2019.73.195-200"},{"key":"e_1_2_7_21_1","first-page":"163","article-title":"Feasibility and value of non\u2010locking retrograde nail vs. locking retrograde nail in fixation of distal third femoral shaft fractures: radiographic, bone densitometry and clinical outcome assessments","volume":"17","author":"Bisaccia M","year":"2020","journal-title":"Med Glas (Zenica)"},{"key":"e_1_2_7_22_1","first-page":"16","article-title":"The challenge of nonunion and malunion in distal femur surgical revision","author":"Rollo G","year":"2019","journal-title":"Med Glas (Zenica)"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-016-0755-5"},{"key":"e_1_2_7_24_1","first-page":"498","article-title":"Surgical treatment of multi\u2010fragmentary segmental femur shaft fractures with ORIF and bone graft versus MIPO: a prospective control\u2010group study","volume":"17","author":"Rollo G","year":"2020","journal-title":"Med Glas (Zenica)"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-015-2829-0"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2005.10.006"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199404000-00020"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100180121"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.19.00584"},{"key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"244","DOI":"10.55095\/achot2011\/038","article-title":"Femoral lengthening. 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