{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:23:21Z","timestamp":1781612601908,"version":"3.54.5"},"reference-count":46,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Whether there was clinical superiority for the single\u2010radius prosthesis over the multi\u2010radius prothesis in total knee arthroplasty (TKA) still remains to be clarified. We updated a meta\u2010analysis including prospective randomized controlled trials (RCTs) to compare the clinical prognosis of patients receiving single\u2010radius TKA (SR\u2010TKA) or multi\u2010radius TKA (MR\u2010TKA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched the databases of PubMed, Web of Science, EMBASE, Cochrane Library, MEDLINE for eligible RCTs. Two reviewers evaluated the study quality according to the Risk of Bias tool of the Cochrane Library and extracted the data in studies individually. The extracted data included the baseline data and clinical outcome. The baseline data include the author's name, country, and year of included studies, the name of knee prosthesis used in studies, sample size, follow\u2010up time, and BMI of patients. The clinical data comprised primary indicators including postoperative knee range of motion (ROM), sit\u2010to\u2010stand rest, severe postoperative scorings, such as visual analog scale (VAS), American Knee Society knee score (AKS), Oxford knee scoring (OKS), and SF\u201036 Quality of Life Scale, as well as various secondary indicators of complications including anterior knee pain, postoperative infection, aseptic prosthesis loosening, and prosthesis revision. The data analysis was performed using Review Manager 5.3 software and STATA 12.0. The sensitivity analysis was performed using STATA 12.0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 13 RCTs, along with 1720 patients and 1726 knees, were finally included in our present meta\u2010analysis. We found that patients in SR\u2010TKA group performed better in the sit\u2010to\u2010stand test (OR\u00a0=\u00a01.89, 95% CI: 1.05\u20133.41, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.03) and satisfaction evaluation (OR\u00a0=\u00a03.27, 95% CI: 1.42\u20137.53, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.005), which were only evaluated in two included RCTs. While no significant difference was found between SR\u2010TKA and MR\u2010TKA groups in terms of postoperative ROM, VAS scoring, AKS scoring, SF\u201036 scoring, OKS scoring, and various complications including anterior knee pain, postoperative infection, aseptic prosthesis loosening, and prosthesis revision.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In conclusion, our present meta\u2010analysis indicated that SR implants were noninferior to MR implants in TKA, and SR implants could be an alternative choice over MR implants, since patients after SR\u2010TKA felt more satisfied and performed better in the sit\u2010to\u2010stand test, with no significant difference in complications between SR\u2010TKA and MR\u2010TKA groups. While more relevant clinical trials with long\u2010term follow\u2010up time and specific tests evaluating the function of knee extension mechanism should be carried out to further investigate the clinical performance of SR implants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13391","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T10:05:48Z","timestamp":1659607548000},"page":"2085-2095","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of <scp>Single\u2010Radius<\/scp> with <scp>Multiple\u2010Radius<\/scp> Femur in Total Knee Arthroplasty: A <scp>Meta\u2010Analysis<\/scp> of Prospective Randomized Controlled Trials"],"prefix":"10.1111","volume":"14","author":[{"given":"Ting","family":"Lei","sequence":"first","affiliation":[{"name":"Department of Orthopeadic Surgery Xiangya Hospital Central South University  Changsha 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