{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T07:55:51Z","timestamp":1774770951109,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Infection after total knee arthroplasty (TKA) is a rare but devastating complication. Different types of spaces have been used in two\u2010stage revision. The study aimed to evaluate the effect of autoclaved femoral and tibial components as spacers for treating periprosthetic infections after TKA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was performed for 13 patients (five males, eight females) with a mean age of 69\u2009\u00b1\u20096 (range, 57\u201380) years and suffering from periprosthetic infection after TKA. They were treated with unconventional two\u2010stage revision from May 2008 to June 2017. In the first\u2010stage surgery, the autoclaved femoral and tibial components were reimplanted with a new liner as a spacer after a thorough debridement. After 4\u20136\u2009months, the second\u2010stage surgery was performed according to the patients' requirements. The knee society score (KSS) and knee range of motion (ROM) were assessed before and after surgery. The reinfection rate was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean duration of follow\u2010up was 5.7\u2009\u00b1\u20092.1 (range, 3.1\u20138.8) years. Culture\u2010positive infections comprised 69% of the cohort. All patients were able to walk 24 h after the first stage surgery, and the knee ROM could reach 90\u00b0 in 1\u2009week. Two patients (15.4%) experienced an infection recurrence. One patient was reinfected 1\u2009year after the first stage surgery. Another patient developed reinfection 3\u2009years after surgery but did not choose re\u2010revision and died of pneumonia. Only one patient underwent the second stage revision. The remaining 10 patients refused to receive a new prosthesis. At the time of the final follow\u2010up, six patients had slight pain in the knee while walking, and one patient required crutches to walk. There were no signs of prosthesis dislocation, rupture, deep vein thrombosis, pulmonary embolism, or delayed wound healing. No radiolucent lines or osteolysis were found. The mean KSS improved from 51\u2009\u00b1\u200910 (range, 35\u201363) points preoperatively to 79\u2009\u00b1\u20095 (range, 60\u201385) points at the final follow\u2010up. The average ROM before and after the first stage surgery were 62\u00b0\u2009\u00b1\u200929\u00b0 (range, 10\u00b0\u2013100\u00b0) and 104\u00b0\u2009\u00b1\u20099\u00b0 (range, 90\u00b0\u2013120\u00b0) (<jats:italic>t<\/jats:italic>\u00a0=\u00a04.659, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01) respectively. The infection control rate was 84.6%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Reimplantation of the autoclaved original femoral and tibial components as an articulating spacer during the first stage surgery is a valuable addition for treating an infected TKA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13402","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T10:21:07Z","timestamp":1658917267000},"page":"2042-2049","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Mid\u2010term Follow\u2010up Study on the Reimplantation of Autoclaved Femoral and Tibial Components as Spacers for Treating Infected Total Knee Arthroplasty"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9432-2569","authenticated-orcid":false,"given":"Peng","family":"Li","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Longgang District People's Hospital of Shenzhen &amp; The Second Affiliated Hospital of The Chinese University of Hong Kong  Shenzhen China"},{"name":"Department of Orthopedic Surgery, Nanfang Hospital Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiqi","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Longgang District People's Hospital of Shenzhen &amp; The Second Affiliated Hospital of The Chinese University of Hong Kong  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangyang","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Longgang District People's Hospital of Shenzhen &amp; The Second Affiliated Hospital of The Chinese University of Hong Kong  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhanjun","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Nanfang Hospital Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-015-3780-8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.97B10.36475"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2012.04.007"},{"key":"e_1_2_6_5_1","first-page":"449","article-title":"Management of infection at the site of a total knee arthroplasty","volume":"55","author":"Leone JM","year":"2006","journal-title":"Instr Course 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