{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:07:55Z","timestamp":1790838475504,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["grant no. 81960392"],"award-info":[{"award-number":["grant no. 81960392"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>As disc fragment completely loses contact with the parent disc and can migrate in all directions of the epidural space, making it appear similar to schwannoma, it is fairly difficult to make a definitive diagnosis for mimicking tumor discs. The aim of this research is to differentially diagnose mimicking tumor discs and schwannomas using coronal magnetic resonance imaging (MRI) of three\u2010dimensional fast\u2010field echo with water\u2010selective excitation (CMRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Among 76 patients (38 men and 38 women; mean age, 52.88\u2009\u00b1\u200915.80 [range, 18\u201378\u2009years]) who were retrospectively examined in this study, 38 were primarily diagnosed with schwannomas and pathologically diagnosed with mimicking tumor discs after surgery, and 38 were primarily diagnosed with neurogenic tumors and pathologically diagnosed with schwannomas after surgery. Open surgery was performed in all the patients between March 2016 and April 2020. The preliminary diagnosis of all patients was considered an intraspinal tumor based on conventional two\u2010dimensional MRI sequences. After open surgery, the final diagnosis was confirmed to mimic a tumor disc or schwannoma based on postoperative pathology reports. The sensitivity, specificity, and reliability of CMRI and conventional MRI for identifying mimicking tumor discs and schwannomas were compared. Chi\u2010square and McNemar tests were used for statistical analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Symptoms were considerably relieved in all the patients after surgery. Seven patients had grade 1 extensor digitorum longus, triceps surae, or quadriceps femoris muscle strength prior to surgery. No nerve root injury was observed in any of the patients. CMRI showed significantly higher sensitivity (94.74%) and specificity (94.74%) than conventional MRI (71.05% and 92.11%, respectively; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.012\u2009&lt;\u20090.05, and <jats:italic>p<\/jats:italic>\u00a0=\u00a01\u2009&gt;\u20090.05, respectively) for differential identification between mimicking tumor discs and schwannomas. Moreover, CMRI showed a higher reliability (kappa value\u00a0=\u00a00.787) than conventional MRI (kappa value\u00a0=\u00a00.374).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CMRI is a better non\u2010invasive technology for the identification of intraspinal lesions, especially for differentiating between mimicking tumor discs and schwannomas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13458","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T11:10:25Z","timestamp":1667387425000},"page":"3330-3339","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Differential Diagnosis of Mimicking Tumor Discs Using Coronal Magnetic Resonance Imaging of Three\u2010Dimensional Fast\u2010Field Echo with Water\u2010Selective Excitation: A Single Center Retrospective Study"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5180-8646","authenticated-orcid":false,"given":"Jinghong","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of Orthopaedics The Second Affiliated Hospital of Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics The Second Affiliated Hospital of Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwen","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics The Second Affiliated Hospital of Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Radiology The Second Affiliated Hospital of Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingxue","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Radiology The Second Affiliated Hospital of Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Fengcheng People's Hospital  Fengcheng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikuan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics The Second Affiliated Hospital of Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xijuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Paediatrics The Second Affiliated Hospital of Nanchang University  Nanchang 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