{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:50:57Z","timestamp":1747187457685,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Intravascular papillary endothelial hyperplasia (IPEH) is a reactive lesion histopathologically characterized by papillary growth of vascular endothelial cells. IPEH is most commonly found in the skin and subcutaneous tissues of the head, neck, and extremities. Furthermore, it has been reported to occur in oral surgery, but its occurrence in bone is extremely rare.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>We present the case of a 77\u2010year\u2010old man with a chief complaint of left knee arthralgia. The knee joint X\u2010ray showed Kellgren\u2013Lawrence grade 4 osteoarthritis and a mass lesion with decreased permeability within the bone in the medial part of the proximal tibia. Computerized tomography (CT) scan of the left knee showed a localized mass in the left proximal tibia with clear margins and granular internal calcification. The preoperative diagnosis was left knee osteoarthritis and a benign tumor of the left proximal tibia (enchondroma or hemangioma). The patient requested surgical treatment, so left total knee arthroplasty (TKA) and resection of the tumor were performed. The pathology revealed a rare intraosseous IPEH with marked calcification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Since intraosseous IPEH could not be considered from the clinical findings, the pathological diagnosis was the decisive factor. This report showed the world's first case of intraosseous IPEH with marked calcification. Similar to the calcification of intraosseous hemangiomas, we considered the possibility that, in IPEH, the thrombus may fibrosis and organize in concentric circles, causing necrosis at the center and resulting in calcification. TKA was performed on the degenerative knee joint with IPEH, and a good patient outcome was obtained.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13495","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T10:20:05Z","timestamp":1664533205000},"page":"3134-3138","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Unique Surgical Case of Ancient Calcified Intravascular Papillary Endothelial Hyperplasia in the Tibia with Knee Joint Osteoarthritis"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5285-9429","authenticated-orcid":false,"given":"Hironori","family":"Kitajima","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Shioya","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kanazawa Medical University  Ishikawa Japan"},{"name":"Department of Pathology Kanazawa Medical University Hospital  Ishikawa Japan"},{"name":"Department of Pathology Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rie","family":"Kadoguchi","sequence":"additional","affiliation":[{"name":"Department of Pathology Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kanazawa Medical University  Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hinako","family":"Sawano","sequence":"additional","affiliation":[{"name":"Department of Pathology Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsutaka","family":"Yonezawa","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Hiromura","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuteru","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Nojima","sequence":"additional","affiliation":[{"name":"Department of Pathology, Graduate School of Medical Sciences Kanazawa University  Ishikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2662-0024","authenticated-orcid":false,"given":"Sohsuke","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kanazawa Medical University  Ishikawa Japan"},{"name":"Department of Pathology Kanazawa Medical University Hospital  Ishikawa Japan"},{"name":"Department of Pathology Kanazawa Medical University Himi Municipal Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"e_1_2_13_2_1","first-page":"517","article-title":"Hemangioendotheliome vegetant intravasculaire","volume":"93","author":"Masson P","year":"1923","journal-title":"Bull Soc Anat Paris"},{"key":"e_1_2_13_3_1","first-page":"441","article-title":"Intravascular papillary endothelial hyperplasia","volume":"100","author":"Clearkin KP","year":"1976","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198312000-00004"},{"key":"e_1_2_13_5_1","article-title":"Intravascular papillary endothelial hyperplasia of the mandible: a rare entity","volume":"33","author":"Luigi L","year":"2021","journal-title":"J Craniofac Surg"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/15513815.2020.1852462"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/02688697.2019.1597832"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0000000000002364"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03459.x"},{"key":"e_1_2_13_10_1","first-page":"900","article-title":"Japanese Orthopaedic Association knee scoring system","volume":"62","author":"Koshino T","year":"1988","journal-title":"J Jpn Orthop Assoc"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2011.02281.x"},{"key":"e_1_2_13_12_1","first-page":"259","article-title":"Florid extravascular papillary endothelial hyperplasia (Masson's pseudoangiosarcoma) presenting as a soft\u2010tissue sarcoma","volume":"117","author":"Pins MR","year":"1993","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-020-03527-4"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-3401381"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198404000-00049"}],"container-title":["Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.13495","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/os.13495","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.13495","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T17:15:52Z","timestamp":1692638152000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/os.13495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,30]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/os.13495"],"URL":"https:\/\/doi.org\/10.1111\/os.13495","archive":["Portico"],"relation":{},"ISSN":["1757-7853","1757-7861"],"issn-type":[{"type":"print","value":"1757-7853"},{"type":"electronic","value":"1757-7861"}],"subject":[],"published":{"date-parts":[[2022,9,30]]},"assertion":[{"value":"2022-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}