{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T21:11:47Z","timestamp":1777410707896,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072518"],"award-info":[{"award-number":["82072518"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Emery\u2013Dreifuss muscular dystrophy (EDMD) is an uncommon, gradually progressive X\u2010linked myopathy, and it could result in rigid spinal deformity. Only a few case reports have described surgical treatment of cervical hyperlordosis and thoracolumbar kyphoscoliosis secondary to EDMD. We report a rare case of EDMD to present the surgical strategies of severe cervical hyperlordosis and thoracolumbar kyphoscoliosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>The patient was a 22\u2010year\u2010old man with EDMD who had severe cervical hyperlordosis and thoracolumbar kyphoscoliosis. A posterior spinal fusion from T9\u2010S2 was performed to correct the thoracolumbar kyphoscoliosis at the age of 21\u2009years. Six months later, with an anterior C7\u2010T1 closing wedge bone\u2010disc\u2010bone osteotomy and a posterior\u2013anterior\u2013posterior cervicothoracic fusion from C4\u2010T4, the cervical deformity was corrected, thus achieving a horizontal gaze. During 1.5\u2010year follow\u2010up, no loss of correction was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cervical posterior\u2013anterior\u2013posterior closing\u2010wedge osteotomy combined with long fusion at thoracolumbar spine can be a reliable surgical technique to correct severe spine deformity in EDMD. This two\u2010stage revision surgical strategy can help restore a horizontal gaze on the basis of a balanced trunk. Cervical deformity in such patients should be corrected in the first stage considering its role as a \u201cdriver\u201d of the global spine deformity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13526","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T10:53:12Z","timestamp":1666003992000},"page":"3448-3454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Surgical Treatment for Severe Cervical Hyperlordosis and Thoracolumar Kyphoscoliosis with <scp>Emery\u2013Dreifuss<\/scp> Muscular Dystrophy: A Case Report and Literature Review"],"prefix":"10.1111","volume":"14","author":[{"given":"Ziyang","family":"Tang","sequence":"first","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital The Clinical College of Nanjing Medical University  Nanjing 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