{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:23:01Z","timestamp":1790310181922,"version":"4.1.0"},"reference-count":51,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"publisher","award":["2019A1515011290"],"award-info":[{"award-number":["2019A1515011290"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"publisher","award":["2019A1515110983"],"award-info":[{"award-number":["2019A1515110983"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001319"],"award-info":[{"award-number":["82001319"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102568"],"award-info":[{"award-number":["82102568"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172432"],"award-info":[{"award-number":["82172432"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Enhanced recovery after surgery (ERAS) has been successfully adopted for the improvement of medical quality and efficacy in many diseases, but the effect thereof for ankle fracture patients can vary. The aim of the present study was to explore the short\u2010term postoperative outcomes of ERAS among ankle fracture patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present study was a retrospective cohort study conducted between January 2019 and May 2019. One hundred and sixty ankle fracture participations (58 males and 102 females, aged 41.71\u2009\u00b1\u200914.51\u2009years) were included. The participants treated with open reduction and internal fixation were divided into two groups (non\u2010ERAS vs. ERAS) depending on whether ERAS was applied. Postoperative outcomes included American Orthopedic Foot and Ankle Society (AOFAS) score, length of stay (LOS), hospital cost, complications, and consumption of opioids. To assess the association between the groups and outcomes, generalized estimating equation (GEE) modeling and multivariable linear regression analysis were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average follow\u2010up periods of the participations were 24\u00a0months postoperatively. No significant differences were detected between the non\u2010ERAS group and ERAS group with respect to the demographic of patients in terms of gender, age, Danis\u2010Weber classification of fracture, dislocation of ankle joint, and comorbidity (<jats:italic>P &gt;<\/jats:italic>\u00a00.05). Significant differences in terms of a higher AOFAS score were found in the ERAS group compared with the non\u2010ERAS group (6.73, 95% CI, 5.10\u20138.37, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) at 3\u2009months postoperatively (PO3M) and (4.73, 95% CI, 3.02\u20136.45, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) at 6\u2009months postoperatively (PO6M). However, similar AOFAS scores were found at 12\u00a0months postoperatively (PO12M) (0.28, 95% CI, \u22120.32 to 0.89, <jats:italic>P &gt;<\/jats:italic>\u00a00.05) and at 24\u00a0months postoperatively (PO24M) (0.56, 95% CI, \u22120.07 to 1.19, <jats:italic>P &gt;<\/jats:italic>\u00a00.05). Additionally, the GEE analysis and group\u2010by\u2010time interaction of AOFAS score revealed that the ERAS protocol could facilitate faster recovery for ankle fracture patients, with higher PO3M and PO6M (both <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). At the same time, significant differences in terms of a shorter length of stay (\u22123.19, 95% CI, \u22124.33 to \u22122.04, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01) and less hospital cost (\u22126501.81, 95% CI, \u221210955.21 to \u22122048.42, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01) were found in the ERAS group compared with the non\u2010ERAS group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>By reducing LOS and hospital cost, the ERAS protocol might improve the medical quality and efficacy. The present study can provide a realistic evaluation and comparison of the ERAS protocol among ankle fracture patients, and ultimately guide clinical decision making.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13621","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T09:10:10Z","timestamp":1674205810000},"page":"766-776","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Short\u2010Term Outcomes of Enhanced Recovery after Surgery (<scp>ERAS<\/scp>) for Ankle Fracture Patients: A Single\u2010Center Retrospective Cohort Study"],"prefix":"10.1111","volume":"15","author":[{"given":"Yuefeng","family":"Yao","sequence":"first","affiliation":[{"name":"Department of Bone &amp; Joint Surgery Peking University Shenzhen Hospital  Shenzhen China"},{"name":"National &amp; Local Joint Engineering Research Center of Orthopaedic Biomaterials Peking University Shenzhen Hospital  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Bone &amp; Joint Surgery Peking University Shenzhen Hospital  Shenzhen China"},{"name":"National &amp; Local Joint Engineering Research Center of Orthopaedic Biomaterials Peking University Shenzhen Hospital  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Renal Division, Peking University Shenzhen Hospital Peking University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6447-2443","authenticated-orcid":false,"given":"Su","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Bone &amp; Joint Surgery Peking University Shenzhen Hospital  Shenzhen China"},{"name":"National &amp; Local Joint Engineering Research Center of Orthopaedic Biomaterials Peking University Shenzhen Hospital  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixiao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Bone &amp; 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