{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:10:29Z","timestamp":1785841829044,"version":"3.56.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Autogenic bone grafts have shown successful fusion rates in the treatment of degenerative lumbar disorders, but taking too many autogenic bones may result in donor site ischemia or infection. This study aimed to evaluate the outcomes of single\u2010level oblique lumbar interbody fusion (OLIF) using pure allograft combined with posterior pedicle screw instrumentation through the Wiltse approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective case analysis was performed on a series of consecutive patients who received a single\u2010level OLIF procedure combined with posterior pedicle screw instrumentation through the Wiltse approach between July 1, 2017, and December 31, 2019, in which pure allogenic bone graft was used and filled in the large window of the cage. The patients were followed up as scheduled at 1\u2009day and 3, 6, 12, 24\u00a0months after operation. Clinical outcome was assessed by multiple questionnaires, including Oswestry disability index (ODI), Japanese Orthopaedic Association (JOA) score rating system, short form\u201036 health survey (SF\u201036), and visual analog scale (VAS) for low back pain. Radiographic outcome was evaluated by measuring the parameters such as disc height, lumbar lordosis, and segmental angle on the standard standing lateral radiographs, and the space angle of the fusion level on the dynamic views of the lateral radiographs. Subsidence of the cage and intervertebral fusion status were evaluated on both the radiographic and CT scan images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 34 patients were finally included in this study. At 2\u2010year follow\u2010up, the VAS for low back pain, ODI, JOA, and SF\u201036 scores all had significant improvement (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Substantial increase of anterior and posterior disc heights was observed (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Both lumbar lordosis and segmental angle became larger (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). No visible change of the space angle of the fusion level was found on the dynamic views. The 1\u2010year fusion rate of 73.5% on CT scans proceeded to 82.4% at 2\u2010year follow\u2010up. The fusion rate was as high as 91.2% according to Bridwell interbody fusion grading system on radiographic images. The clinical outcomes in patients with incomplete fusion were just as good as those with complete fusion. The six patients with cage subsidence had higher ODI (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and lower JOA (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and SF\u201036 PCS (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.011) scores than those without cage subsidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of pure allograft in single\u2010level OLIF resulted in an acceptable fusion rate and satisfactory clinical effect at 2\u2010year follow\u2010up. Supplementation of posterior pedicle screw through the minimally invasive Wiltse approach ensured the favorable outcomes both clinically and radiographically.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13657","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T07:33:38Z","timestamp":1675150418000},"page":"801-809","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Acceptable Fusion Rate of Single\u2010Level <scp>OLIF<\/scp> Using Pure Allograft Combined with Posterior Instrumentation through the Wiltse Approach: A 2\u2010Year Follow\u2010Up Study"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3579-5910","authenticated-orcid":false,"given":"Qingyin","family":"Xu","sequence":"first","affiliation":[{"name":"Spine Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3051-9183","authenticated-orcid":false,"given":"Zeyu","family":"Lu","sequence":"additional","affiliation":[{"name":"Spine Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengbo","family":"Chen","sequence":"additional","affiliation":[{"name":"Spine Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[{"name":"Spine Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinfeng","family":"Zheng","sequence":"additional","affiliation":[{"name":"Spine Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengdan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Spine Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leisheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Spine Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199703150-00023"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4184\/asj.2015.9.4.565"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000703"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001650"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2016.10.074"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000002139"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-4170-0"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0b013e3181ecf995"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-017-0927-8"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200501000-00010"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2018.03.24"},{"issue":"7","key":"e_1_2_10_13_1","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1007\/s00586-016-4414-7","article-title":"A prospective clinical and radiographic 12\u2010month outcome study of patients undergoing single\u2010level anterior cervical discectomy and fusion for symptomatic cervical degenerative disc disease utilizing a novel viable allogeneic, cancellous, bone matrix (trinity evolution\u2122) with a comparison to historical controls","volume":"25","author":"Vanichkachorn J","year":"2016","journal-title":"Eur Spine J"},{"issue":"2","key":"e_1_2_10_14_1","first-page":"S158","article-title":"Outcomes of allogenic cages in anterior and posterior lumbar interbody fusion","volume":"10","author":"Janssen ME","year":"2001","journal-title":"Eur Spine J"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-020-06389-3"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-020-06667-2"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-018-0743-z"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200011150-00017"},{"issue":"3","key":"e_1_2_10_19_1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s00776-009-1337-8","article-title":"JOA Back pain evaluation questionnaire (JOABPEQ)\/JOA cervical myelopathy evaluation questionnaire (JOACMEQ). The report on the development of revised versions. April 16, 2007. The Subcommittee of the Clinical Outcome Committee of the Japanese Orthopaedic association on low Back pain and cervical myelopathy evaluation","volume":"14","author":"Fukui M","year":"2009","journal-title":"J Orthop Sci"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199401000-00004"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(05)70381-9"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.07.459"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199506020-00014"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/os.12625"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31821f50de"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-016-3124-4"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2016.10.026"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.14444\/5013"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e318171927c"},{"issue":"1","key":"e_1_2_10_30_1","first-page":"53","article-title":"Comparative study between mini\u2010open TLIF via Wiltse's approach and conventional open TLIF in lumbar degenerative diseases","volume":"22","author":"Li HJ","year":"2018","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_10_31_1","first-page":"219256822199209","article-title":"The influence of endplate morphology on cage subsidence in patients with stand\u2010alone oblique lateral lumbar Interbody fusion (OLIF)","author":"Hu Z","year":"2021","journal-title":"Global Spine J"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/21925682211067210"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-3844-y"}],"container-title":["Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.13657","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/os.13657","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.13657","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T03:47:39Z","timestamp":1692330459000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/os.13657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,30]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1111\/os.13657"],"URL":"https:\/\/doi.org\/10.1111\/os.13657","archive":["Portico"],"relation":{},"ISSN":["1757-7853","1757-7861"],"issn-type":[{"value":"1757-7853","type":"print"},{"value":"1757-7861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,30]]},"assertion":[{"value":"2022-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}