{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T08:29:05Z","timestamp":1770539345789,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>At present, the most commonly used filler polymethyl methacrylate (PMMA) has the disadvantages of monomer toxicity, heat and leakage, and cannot be applied in young people. Therefore, finding a minimally invasive and good tissue\u2010compatible alternative material has been a research hotspot in spine surgery in recent years. The aim of this study is to explore whether the memory alloy stent can avoid the complications of bone cement or not.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Four non\u2010adjacent vertebral bodies of the thoracic and lumbar spine in the 18 10\u2010month\u2010old pigs were selected as the surgical site and were randomly divided into the scaffold group and the bone cement group. The memory alloy scaffold and PMMA (polymethyl methacrylate) bone cement were placed via percutaneous puncture, and intraoperative fluoroscopy and micro\u2010CT were used to observe the changes in the height of scaffolds and bone cement in the vertebral body immediately, 6\u2009weeks, and 12\u2009weeks after operation, the microstructural parameters of the bone trabeculae (bone volume fraction, bone surface volume ratio, bone trabeculae number) were also measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The memory alloy stent could expand in the vertebral body, and its height gradually increased with time; additionally, the height of the bone cement mass did not change with time (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.00). New bone trabeculae could grow into the scaffold along the gap, and the volume fraction of bone, the volume ratio of bone surface area, and the number of bone trabeculae increased gradually (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.00). However, the volume fraction of bone, the volume ratio of bone surface area, and the number of trabeculae in the cement block decreased gradually (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.00).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Memory alloy scaffolds have dynamic expansion characteristics in vivo, which can effectively avoid the complications of bone cement. Thus, it is beneficial to explore this minimally invasive treatment for vertebral compression fractures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13680","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T06:04:42Z","timestamp":1676613882000},"page":"1028-1036","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Preliminary Study on the Morphological Changes of an <scp>NiTi<\/scp>\u2010Shaped Memory Alloy Stent in the Vertebral Body"],"prefix":"10.1111","volume":"15","author":[{"given":"Li","family":"Qiaoling","sequence":"first","affiliation":[{"name":"Nursing Department The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren","family":"Zhiwei","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhang","family":"Bobo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1185-9924","authenticated-orcid":false,"given":"Yang","family":"Yimin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1553350619869535"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-019-05101-8"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.07.153"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-018-4804-2"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000002971"},{"key":"e_1_2_10_7_1","first-page":"209","article-title":"The role of unilateral balloon kyphoplasty for the treatment of patients with OVCFS: a systematic review and meta\u2010analysis","volume":"21","author":"Guang\u2010Heng X","year":"2018","journal-title":"Pain Physician"},{"issue":"3","key":"e_1_2_10_8_1","first-page":"7","article-title":"An initial imaging analysis of shape memory alloy expandable vertebra stent expanding experiment results in vertebral bodies","volume":"7","author":"Xiaoyong L","year":"2010","journal-title":"Orthop Biomech Mater Clin Study"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/0953-8984\/22\/31\/316004"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1088\/0953-8984\/23\/45\/456004"},{"issue":"21","key":"e_1_2_10_11_1","first-page":"694","article-title":"Biodegradable shape memory polymers in medicine","volume":"6","author":"Peterson Gregory I","year":"2017","journal-title":"Adv Healthcare Mater"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep37475"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13239-018-0369-7"},{"key":"e_1_2_10_14_1","first-page":"508","article-title":"Placement of a shape\u2010memory alloy intraurethral catheter (Memokath) using transrectal ultrasonography and fluoroscopy","volume":"100","author":"Tomonori M","year":"2009","journal-title":"Nihon Hinyokika Gakkai Zasshi"},{"key":"e_1_2_10_15_1","first-page":"166","article-title":"Application of a shape\u2010memory alloy concentrator in displaced patella fractures: technique and long\u2010term results","volume":"30","author":"Yuntong Z","year":"2017","journal-title":"J Knee Surg"},{"issue":"9","key":"e_1_2_10_16_1","first-page":"16899","article-title":"The implantation of a nickel\u2010titanium shape memory alloy ameliorates vertebral body compression fractures: a cadaveric study","volume":"8","author":"Bo C","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000229254.89952.6b"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181b7cc5d"}],"container-title":["Orthopaedic 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