{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T19:28:49Z","timestamp":1770578929561,"version":"3.49.0"},"reference-count":52,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82100323"],"award-info":[{"award-number":["82100323"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Using a fibula autograft (FA) to reconstruct defects after <jats:italic>en bloc<\/jats:italic> resection of giant cell tumor of bone (GCTB) in the distal radius is classic but has high complication rates. We describe a novel reconstruction method employing the cooperative application of LARS\u00ae and a 3D\u2010printed prosthesis (L\u2010P) and investigate whether it improves postoperative outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From April 2015 to August 2022, 14 patients who underwent the cooperative L\u2010P reconstruction method after <jats:italic>en bloc<\/jats:italic> resection of distal radial GCTBs and 31 patients who received FA reconstruction were enrolled as two retrospective cohorts in this comparative study. The properties of the implants and critical surgical techniques were elaborated in the L\u2010P group. Preoperative function, intraoperative data, and postoperative clinical, functional, and radiographic outcomes of all patients were recorded and compared between the two groups. The grip strength and range of wrist motion, including extension, flexion, radial deviation, and ulnar deviation, were measured. The Mayo modified wrist and Musculoskeletal Tumor Society scores were chosen to assess wrist function and surgical functional outcomes, respectively. Kaplan\u2013Meier curves were generated to analyze the significant differences in complication rates and implant survival between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In both groups, all 45 patients underwent the operation without complication with similar average osteotomy lengths and bleeding volumes, while a shorter operative duration was achieved in the L\u2010P group (201.43\u2009\u00b1\u200922.87 min vs. 230.16\u2009\u00b1\u200951.44 min, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.015). At a mean follow\u2010up of 40.42\u2009\u00b1\u200918.43\u00a0months (range, 14\u201372\u00a0months), both reconstruction methods effectively ameliorated postoperative function. Patients who received L\u2010P showed higher postoperative modified Mayo wrist scores (81.43\u2009\u00b1\u20095.49 vs. 71.13\u2009\u00b1\u200916.10, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.003), Musculoskeletal Tumor Society scores (27.64\u2009\u00b1\u20091.34 vs. 25.06\u2009\u00b1\u20092.95, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.004), and grip strength on the normal side (68.71%\u2009\u00b1\u20098.00% vs. 57.81%\u2009\u00b1\u200912.31%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.005) than the FA group. Better wrist extension (63.21\u00b0\u2009\u00b1\u20098.99\u00b0 vs. 45.32\u00b0\u2009\u00b1\u200914.53\u00b0, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and flexion (45.36\u00b0\u2009\u00b1\u20097.90\u00b0 vs. 30.48\u00b0\u2009\u00b1\u200912.07\u00b0, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) were also observed in the L\u2010P group. The complication rate was significantly higher in the FA group (29\/31, 93.55%) than in the L\u2010P group (1\/14 7.14%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The L\u2010P group showed higher implant survival than the FA group, but the difference was not statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The cooperative application of LARS\u00ae and 3D\u2010printed prostheses is an effective modality for reconstructing musculoskeletal defects after <jats:italic>en bloc<\/jats:italic> resection of distal radial GCTBs, which can improve functional outcomes, diminish complication rates, and promote wrist joint stability and motion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13722","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T14:01:50Z","timestamp":1681999310000},"page":"1521-1533","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Primary Cooperative Application of a <scp>LARS<\/scp>\u00ae Tube and <scp>3D<\/scp>\u2010Printed Prosthesis for Reconstruction of the Distal Radius after <i>en bloc<\/i> Resection of Giant Cell Tumor of Bone: A Comparative Retrospective Study"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6044-9959","authenticated-orcid":false,"given":"Xianhao","family":"Shao","sequence":"first","affiliation":[{"name":"Department of Orthopaedics Shandong Provincial Hospital Affiliated to Shandong First Medical University  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Qilu Hospital, Cheeloo College of Medicine, Shandong University  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianmin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Qilu Hospital, Cheeloo College of Medicine, Shandong University  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaorui","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Qilu Hospital, Cheeloo College of Medicine, Shandong University  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Qilu Hospital, Cheeloo College of Medicine, Shandong University  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Chu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Fuwai Hospital, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"},{"name":"Department of Cardiac Surgery Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College  Beijing 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