{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:55:54Z","timestamp":1793332554628,"version":"4.5.0"},"reference-count":45,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T00:00:00Z","timestamp":1691971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072386"],"award-info":[{"award-number":["82072386"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102521"],"award-info":[{"award-number":["82102521"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Although direct isthmic repair, such as PSVPH, did not affect the mobility of the fixed segment and adjacent segment, it has a relatively low rate of isthmic fusion compared with conventional fusion. The Isobar TTL dynamic internal fixation system has been widely used in clinical practice and has achieved satisfactory clinical results. However, the use of the Isobar TTL system in combination with direct isthmic repair for lumbar spondylolysis has rarely been reported. The aim of this study was to compare the clinical and radiologic outcomes between patients who underwent Isobar TTL system and PSVPH with direct repair of defect for lumbar spondylolysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Stepwise propensity score matching (PSM) for age and sex were performed to keep comparable clinical data between groups in this retrospective and matched\u2010pair case control study. A total of 50 patients diagnosed with lumbar spondylolysis underwent surgical implantation of the Isobar TTL group (<jats:italic>n<\/jats:italic>\u2009=\u200925) or PSVPH group (<jats:italic>n<\/jats:italic>\u2009=\u200925) from June 2009 to June 2016. Clinical outcomes were assessed using the Oswestry disability index (ODI), and visual analog score (VAS). Radiographic evaluations included range of motion (ROM) and the disc heights of stabilized segment and adjacent segment, adjacent segment degeneration (ASD) and bony fusion. Three\u2010dimensional reconstruction of lumbar CT scan was obtained to evaluate bone fusion of the isthmic at final follow\u2010up. The independent Student's <jats:italic>t<\/jats:italic> test and chi\u2010square test were applied to compare the differences between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 25 patients from TTL group were matched to 25 patients in PSVPH group for age, sex, body mass index (BMI), defect side, spondylolisthesis meyerding, and follow\u2010up duration. The intervertebral space height (IH) of stabilized segment at postoperative 1 week and final follow\u2010up in the TTL group was higher than those in the PSVPH group, respectively (<jats:italic>P<\/jats:italic>\u2009=\u20090.030; <jats:italic>P<\/jats:italic>\u2009=\u20090.013). The ROM of stabilized segment at final follow\u2010up in the TTL group was significantly lower than that in the PSVPH group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The bony fusion rate at the final follow\u2010up was 88.0% (22\/25 cages) in the TTL group and 80.0% (20\/25 cages) in the PSVPH group. The ODI score at final follow\u2010up in the TTL group was significantly lower than that in the PSVPH group (<jats:italic>P<\/jats:italic>\u2009=\u20090.007).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Overall, our data suggest that the Isobar TTL system outcomes are comparable to those in the PSVPH, with a similar high bony fusion rate as PSVPH, especially its wider indications as a new surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13837","type":"journal-article","created":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T03:44:33Z","timestamp":1692071073000},"page":"2582-2590","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical Outcomes of Isobar <scp>TTL<\/scp> System with Isthmic Bone Grafting and Pedicle Screw\u2010Vertebral Plate Hook with Direct Repair of Defect for Lumbar Spondylolysis: A Matched\u2010Pair Case Control Study"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3331-3674","authenticated-orcid":false,"given":"Qiujiang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowen","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingquan","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiliang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2377-0740","authenticated-orcid":false,"given":"Yueming","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University  Chengdu 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