{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:45:33Z","timestamp":1791477933251,"version":"4.3.4"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in\u2010hospital death of patients. This study adopted a case\u2010control study to explore the risk factors of in\u2010hospital death in elderly patients with chronic ischemic diabetic foot after receiving TTT treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 54 patients were included in the study from January 1, 2017 to April 30, 2021, by being paired with the cases in case group with their demographic data and results of blood routine, liver and kidney function. There were nine patients in case group with six male and three male. Forty\u2010five patients were selected in control group according to gender and diabetes type with 30 male and 15 female. Single factor logics regression analysis was used to explore the risk factors and odd ratios (OR) of in\u2010hospital death in patients. The nomogram and decision curve analysis (DCA) had been done by R Studio software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study found that age, course of diabetic foot, small dense low\u2010density Lipoprotein (smLDL), homocysteine (Hcy), superoxide dismutase (SOD), and prealbumin (PA) were risk factors for in\u2010hospital death of patients. The smLDL had the highest risk. The nomogram showed that PA accounted for the largest proportion in the death risk factors. The results of DCA proved that above six risk factors were the risk factors for patients with TEXAS Stage 3 and 4 diabetic foot ulcers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the future diagnosis and TTT treatment for diabetic foot ulcers, doctors need to pay close attention to age, course of diabetic foot, smLDL, Hcy, SOD, and PA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.13908","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T03:20:27Z","timestamp":1697080827000},"page":"3272-3278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Analysis of Risk Factors for in\u2010hospital Death in Elderly Patients with <scp>TEXAS<\/scp> Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case\u2013Control Study"],"prefix":"10.1111","volume":"15","author":[{"given":"Xiaofang","family":"Ding","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Beijing Chaoyang Hospital Capital Medical University  Beijing China"},{"name":"Beijing Longfu Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusong","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery China\u2010Japan Friendship Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1829-3852","authenticated-orcid":false,"given":"Hailin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedics, Peking University People's Hospital Peking University  Beijing China"},{"name":"National Center for Trauma medicine  Beijing China"},{"name":"Diabetic Foot Treatment Centre, Peking University People's Hospital Peking University  Beijing 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