{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T08:48:35Z","timestamp":1788684515092,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,3,31]],"date-time":"2024-03-31T00:00:00Z","timestamp":1711843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902742"],"award-info":[{"award-number":["81902742"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Percutaneous CT\u2010guided radiofrequency ablation (CT\u2010RFA) is a widely accepted procedure for treatment of osteoid osteomas. However, the application of CT\u2010RFA was restricted as a result of some drawbacks, such as radiation exposure, and inconvenience in general anesthesia. The primary aim of this study is to evaluate the safety and efficacy of intra\u2010operative TiRobot\u2010assisted percutaneous RFA of osteoid osteomas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed 21 medical files of patients who were treated with percutaneous RFA of osteoid osteomas guided by the TiRobot system in our institution between March 2021 and April 2022. The three\u2010dimensional images obtained by a 3D C\u2010arm intra\u2010operatively were sent to the TiRobot system. The puncture point and trajectory were designed. Then the guide pin was positioned to the lesion with the assistance of TiRobot and the biopsy sheath was inserted into the lesion through the guide pin. The tumor was biopsied for pathological examination. Then the RFA needle was inserted into the nidus through the biopsy sheath for thermal ablation. Data were extracted on the associated complications, the reduction in pain at 1\u2009month and 1\u2009year postoperatively assessed by the visual analogue scale (VAS). A paired <jats:italic>t<\/jats:italic>\u2010test was used to compare the pre\u2010operative and post\u2010operative VAS scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patients included 17 males and four females with a mean age of 19.5\u2009\u00b1\u200910.4\u2009years (range 3\u201345\u2009years). Lesions were located on the femur in nine cases, on the tibia in nine cases, on the humerus in one case, on the calcaneus in one case, and on the acetabulum in one case. TiRobot\u2010assisted percutaneous RFA was successfully performed on all 21 patients. There was no intra\u2010operative or post\u2010operative complications observed. Pathological diagnosis of osteoid osteoma was obtained in 11 patients, but the other 10 cases were not pathologically diagnosed. The mean follow\u2010up time was 18.8\u2009months (range: 12\u201326\u2009months).Post\u2010operative VAS scores were reduced significantly in all cases. The mean VAS score decreased from 6.5 pre\u2010operatively to 0.5 at 1\u2009month post\u2010operatively and to 0.1 at 1\u2009year post\u2010operatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>As a reliable technique for localizing and resection of nidus, TiRobot\u2010assisted percutaneous RFA is a safe and effective option for the treatment of osteoid osteomas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.14043","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T02:38:43Z","timestamp":1711939123000},"page":"1246-1251","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["<scp>Robot\u2010assisted<\/scp> Percutaneous Radiofrequency Ablation for the Treatment of Osteoid Osteomas"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7335-3033","authenticated-orcid":false,"given":"Ka","family":"Li","sequence":"first","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zonghao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiping","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuantong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7928-3853","authenticated-orcid":false,"given":"Zhenfeng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,31]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mop.0000193277.47119.15"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199806000-00005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.188.2.8327712"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2421041404"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2291021053"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20140535"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-019-2963-8"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jos.2018.09.017"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/os.13930"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/os.13972"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/os.13907"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-016-1533-9"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.881852"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-003-2171-6"}],"container-title":["Orthopaedic 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