{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T05:16:54Z","timestamp":1738559814652,"version":"3.35.0"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172381"],"award-info":[{"award-number":["82172381"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Central cord syndrome (CCS) is an incomplete spinal cord injury (SCI) causing severe motor weakness, and timely decompression via surgical intervention facilitates better recovery. Anterior controllable antedisplacement and fusion (ACAF) is a novel decompression technique and achieved satisfactory outcomes in treating cervical degenerated diseases. However, the clinical effects of ACAF on CCS remains unknown. This present study aimed to investigate the clinical outcomes of ACAF for cervical stenosis patients with CCS due to hyperextension injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study, and patients who underwent ACAF due to CCS in our institution from July 2021 to December 2022 were enrolled based on the inclusion and exclusion criteria. All patients underwent x\u2010ray, computed tomography (CT), and magnetic resonance imaging (MRI) before and after surgery. The duration of follow\u2010up was at least 12\u2009months. The radiological parameters included associated pathologies, prevertebral hyperintensity (HI), intramedullary signal intensity (ISI), and Torg\u2013Pavlov ratio (TPR). The cervical stability was also evaluated. Neurological function was assessed using the American Spinal Injury Association (ASIA) grading system and Japanese Orthopaedic Association (JOA) score. The Mann\u2013Whitney <jats:italic>U<\/jats:italic> test was used to compare the clinical outcomes preoperatively and postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Finally, 13 patients (7 male and 6 female) with the minimum of 12\u2010month follow\u2010up were finally enrolled in this study, with the mean age of 56.6\u2009\u00b1\u200912.5\u2009years (range, 39\u201374\u2009years). There were eight patients suffered CCS due to fall, three due to vehicle accident, and two due to diving injuries. The average delay from injury to surgery was 2.23\u2009days (range, 1\u20134\u2009days), and the mean duration of follow\u2010up was 16.1\u2009\u00b1\u20093.5\u2009months. In terms of prevertebral HI and ISI, C4\u2013C6 were the most affected region. In addition, 76.9% (10 of 13) patients were observed to have cervical stenosis indicated by TPR. Associated pathologies were herniated nucleus pulposus (HNP) in five patients, OPLL in three cases, and HNP\u2010osteophyte complexes (HNP\u2010OC) in six patients. At the final follow\u2010up, 13 patients were improved to E. The mean JOA score improved to 15.4\u2009\u00b1\u20091.0, with the recovery rate of 77.0%\u2009\u00b1\u200912.0%. Two patients experienced postoperative dysphagia, two patients had hoarseness, and one patient suffered postoperative hematoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ACAF can be a good option for treating CCS patients due to hyperextension injury with underlying cervical spondylosis and stenosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.14319","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T01:51:23Z","timestamp":1734054683000},"page":"500-512","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anterior Controllable Antedisplacement and Fusion (<scp>ACAF<\/scp>) for Cervical Stenosis Patients With Hyperextension Injury: A Retrospective Study"],"prefix":"10.1111","volume":"17","author":[{"given":"Shuangxi","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery The Center Hospital of Weihai City  Weihai Shandong China"},{"name":"Department of Orthopedic Surgery Changzheng Hospital, Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingying","family":"Miao","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Changzheng Hospital, Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Hospital of the People's Liberation Army  Ningbo Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0272-8383","authenticated-orcid":false,"given":"Kaiqiang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Changzheng Hospital, Navy Medical University  Shanghai China"},{"name":"Department of Orthopedics Naval Medical Center of PLA, Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijuan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Radiology The Second Affiliated Hospital of Naval Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingchuan","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Changzheng Hospital, Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiuyi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Naval Medical Center of PLA, Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangang","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Changzheng Hospital, Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-024-08244-3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200912000-00004"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1971.03180290049006"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198107000-00005"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2023.10.013"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3171\/2023.11.SPINE23789"},{"key":"e_1_2_10_8_1","first-page":"700","article-title":"Treatment of Acute Traumatic Central Cord Syndrome: A Study of North American Trauma Centers","volume":"94","author":"Badhiwala J. 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