{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:20:28Z","timestamp":1778858428442,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Studies evaluating the long\u2010term outcomes of the nano\u2010hydroxyapatite\/polyamide 66 cages (n\u2010<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PA66<\/jats:styled-content>) in treating lower cervical spine fractures have not been reported. The objective is to compare the long\u2010term clinical and radiographic outcomes of titanium mesh cage (<jats:styled-content style=\"fixed-case\">TMC<\/jats:styled-content>) and\u2010<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PA66<\/jats:styled-content> for anterior cervical corpectomy and fusion (<jats:styled-content style=\"fixed-case\">ACCF<\/jats:styled-content>) in the treatment of lower cervical spine fractures and dislocations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This retrospective analysis included 223 patients treated at our hospital between January 2010 and January 2016 who had undergone single\u2010level anterior corpectomy for lower cervical spine fractures and dislocations (with a minimum follow\u2010up of 8\u2009years) using either a <jats:styled-content style=\"fixed-case\">TMC<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u2009=\u2009130) or an n\u2010<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PA66<\/jats:styled-content> cage (<jats:italic>n<\/jats:italic>\u2009=\u200993). The radiographic parameters, including segmental alignment (SA), cage subsidence, plate\u2010to\u2010disc distance, cervical lordosis (CL), intervertebral height, and fusion status, along with clinical metrics such as Japanese Orthopedic Association (<jats:styled-content style=\"fixed-case\">JOA<\/jats:styled-content>) scores and visual analog scale (<jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>) assessments, were systematically analyzed at preoperative, postoperative, and final follow\u2010up intervals for the patients involved in the study. The Chi\u2010Square (<jats:italic>\u03c7<\/jats:italic>\n<jats:sup>2<\/jats:sup>) test for categorical variables and the Student's <jats:italic>t<\/jats:italic>\u2010test for numerical data were used to assess differences between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>The mean follow\u2010up durations for the <jats:styled-content style=\"fixed-case\">TMC<\/jats:styled-content> group and n\u2010<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PA66<\/jats:styled-content> group were9.81\u2009\u00b1\u20092.21 and 9.43\u2009\u00b1\u20090.92\u2009years, respectively. Moreover, final fusion rates were not significantly different between the n\u2010<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PA66<\/jats:styled-content> group and the <jats:styled-content style=\"fixed-case\">TMC<\/jats:styled-content> group (97.8% and 96.9%, respectively). The final cage subsidence was significantly lower in the n\u2010<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PA66<\/jats:styled-content> group (1.56\u2009\u00b1\u20090.88\u2009mm, with 17.6% subsidence of &gt;\u20093\u2009mm) than in the <jats:styled-content style=\"fixed-case\">TMC<\/jats:styled-content> group (2.70\u2009\u00b1\u20092.02\u2009mm, with 36.9% subsidence) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Furthermore, CL, SA, plate\u2010to\u2010disc distance, <jats:styled-content style=\"fixed-case\">JOA<\/jats:styled-content> scores, and <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> scores were not significantly different between the two groups (all <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Within 8\u2009years following single level ACCF surgery, the n\u2010<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PA66<\/jats:styled-content> cage may be better than <jats:styled-content style=\"fixed-case\">TMC<\/jats:styled-content> in anterior cervical construction for treating lower cervical fractures and dislocations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/os.70048","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T10:20:14Z","timestamp":1746094814000},"page":"1742-1748","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Outcomes of N\u2010<scp>HA<\/scp>\/pa66 and Titanium Mesh in the Treatment of Lower Cervical Spine Fractures and Dislocations During an 8\u2010Year Follow\u2010Up Period"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3260-6244","authenticated-orcid":false,"given":"Chen","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery West China Xiamen Hospital, Sichuan University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujie","family":"Hu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases West China Hospital of Stomatology, Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery West China Xiamen Hospital, Sichuan University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangbin","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery West China Xiamen Hospital, Sichuan University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7925-3323","authenticated-orcid":false,"given":"Xi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery West China Hospital, Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-011-1956-6"},{"issue":"1","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"S137","DOI":"10.1227\/01.NEU.0000249224.59494.A0","article-title":"Cervical Corpectomy and Strut Grafting","volume":"60","author":"Douglas A. 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