{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T04:14:44Z","timestamp":1762143284196,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82302685"],"award-info":[{"award-number":["82302685"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study compared the intraoperative neurophysiological monitoring (IONM) data between patients with Marfan syndrome (MFS) scoliosis undergoing posterior spinal correction surgery and those with idiopathic scoliosis (IS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients diagnosed with MFS who underwent posterior spinal correction surgery between January 2018 and December 2023 were reviewed. Patients with IS who underwent posterior spinal correction surgery were randomly selected as the control group. Motor\u2010evoked potentials (MEPs) and somatosensory\u2010evoked potentials (SEPs) were measured separately on the convex and concave sides of the main curve. We recorded IONM failure and asymmetrical SEPs waveforms. For each patient, we assessed the apical vertebral translation, Cobb angle of the main curve, curve pattern, deformity angular ratio (DAR), and global kyphosis. Independent\u2010sample\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test and chi\u2010square tests were conducted to compare differences between the IS and MFS groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 238 girls with IS and 118 patients with MFS scoliosis (45 men and 73 women). The rates of MEPs and SEPs were 95.4% and 93.7% in girls with IS, and 92.4% and 89.8% in patients with MFS scoliosis, respectively. In the MFS group, the average N45 latency, P37 latency, and amplitude of SEPs were 49.5\u2009\u00b1\u20093.9\u2009ms, 39.9\u2009\u00b1\u20093.5\u2009ms, and 2.5\u2009\u00b1\u20091.4\u2009\u03bcV on the convex side and 50.1\u2009\u00b1\u20094.0\u2009ms, 39.9\u2009\u00b1\u20093.5\u2009ms, and 2.4\u2009\u00b1\u20091.3\u2009\u03bcV on the concave side, respectively. The MEP amplitude was 731.7\u2009\u00b1\u2009734.3\u2009\u03bcV on the concave side and 854.3\u2009\u00b1\u2009778.2\u2009\u03bcV on the convex side. Patients in the IS group had lower SEP\u2010N45 and SEP\u2010P37 latencies than the patients in the MFS group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Asymmetrical SEPs were observed in 102 patients in the IS group and 52 patients in the MFS group, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.879). IONM waveform failure was identified in 21 patients in the IS group and 17 patients in the MFS group, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.108). IONM failure was more likely in patients with a larger C\u2010DAR, S\u2010DAR, T\u2010DAR, and Cobb angle of the main curve preoperatively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.017, 0.005, 0.001, and 0.001, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with MFS scoliosis, the success rates of MEPs and SEPs during posterior spinal fusion were 92.4% and 89.8%. Compared to MFS patients, those with IS demonstrated shorter SEP latencies, with similar MEP and SEP amplitudes. MFS patients with higher DAR values and larger Cobb angles of the main curve preoperatively were at a higher risk of IONM failure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/os.70168","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T01:32:00Z","timestamp":1758159120000},"page":"3109-3115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative Neurophysiological Monitoring in Patients With Marfan Syndrome Scoliosis"],"prefix":"10.1111","volume":"17","author":[{"given":"Kaiyi","family":"Cao","sequence":"first","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School  Nanjing China"},{"name":"Department of Orthopaedics The Affiliated Huai'an Hospital of Xuzhou Medical University and the Second People's Hospital of Huai'an  Huai'an Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanyou","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junyin","family":"Qiu","sequence":"additional","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinkun","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zezhang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Qiu","sequence":"additional","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0244-8525","authenticated-orcid":false,"given":"Benlong","family":"Shi","sequence":"additional","affiliation":[{"name":"Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,17]]},"reference":[{"volume-title":"StatPearls","year":"2025","author":"Salik I.","key":"e_1_2_10_2_1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00197061"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200011010-00012"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/000164701753606725"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3182541af3"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200209150-00008"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000003134"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.5152\/j.aott.2022.22053"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/08990220.2020.1850438"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2020.105689"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-021-01045-3"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.07.465"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/os.13353"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43390-023-00703-z"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001547"},{"key":"e_1_2_10_17_1","first-page":"515","article-title":"Spinal and Pelvic Parameters in Marfan's Syndrome and Their Relevance to Surgical Planning","volume":"88","author":"Loubresse C. 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