{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T18:30:34Z","timestamp":1783967434497,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Wide surgical resection is the standard for primary malignant soft tissue and bone tumors, especially when the knee's intra\u2010articular space is involved. Extraarticular Knee Joint Resection (EKJR) aims to remove the knee joint while preserving function. Considering the lack of literature present on these aspects, the purpose of this study is to analyze the data of a series of 30 patients affected by benign aggressive or malignant bone and soft tissue tumors who underwent EKJR with two different resection techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study involved all patients treated with EKJR for tumors between October 2006 and March 2023. Two EKJR techniques were analyzed: Type\u2010A (complete extensor mechanism excision) and Type\u2010B (patellar coronal osteotomy sparing the extensor mechanism). Clinical outcomes, tumor characteristics, and complications were compared between the two techniques. For statistical analyses, the Mann\u2013Whitney test or Kruskal\u2013Wallis test was employed to explore differences between continuous variables. Relationships between categorical variables were assessed using Pearson's Chi\u2010square test or Fisher's exact test. Correlations were evaluated using Spearman's correlation coefficient. Survival analyses were conducted using the Kaplan\u2013Meier method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The cohort included 13 males and 17 females (16 Type\u2010A, 14 Type\u2010B resections). Histologically confirmed intra\u2010articular involvement was found in 26.7% of cases. Late complications included infections and amputations, more frequently in Type\u2010A resections. The 5\u2010year Local Recurrence\u2010Free Survival was 91.5%, Metastasis\u2010Free Survival was 39.5%, and Overall Survival was 47.9%. Type\u2010A resections lead to higher complication rates, including amputation, due to extensive vascular and tissue disruption. Type\u2010B resections, preserving the extensor mechanism, result in better functional outcomes and faster recovery despite some residual weakness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EKJR is oncologically effective but carries significant functional and complication considerations. Type\u2010B resection balances oncological safety and functional preservation, especially for benign aggressive tumors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/os.70224","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T18:41:57Z","timestamp":1767033717000},"page":"335-346","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Extraarticular Knee Joint Resection: Indications, Results, and Complications in a Series of 30 Patients"],"prefix":"10.1111","volume":"18","author":[{"given":"Carmine","family":"Zoccali","sequence":"first","affiliation":[{"name":"Department of Anatomical, Histological, Forensic Medicine and Orthopedic Science University of Rome  Rome Italy"},{"name":"Oncological Orthopedics Department IRCCS \u2013 Regina Elena National Cancer Institute  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4140-738X","authenticated-orcid":false,"given":"Giuseppe Francesco","family":"Papalia","sequence":"additional","affiliation":[{"name":"Oncological Orthopedics Department IRCCS \u2013 Regina Elena National Cancer Institute  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Cepparulo","sequence":"additional","affiliation":[{"name":"Department of Anatomical, Histological, Forensic Medicine and Orthopedic Science University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Baldi","sequence":"additional","affiliation":[{"name":"Oncological Orthopedics Department IRCCS \u2013 Regina Elena National Cancer Institute  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Sperati","sequence":"additional","affiliation":[{"name":"Oncological Orthopedics Department IRCCS \u2013 Regina Elena National Cancer Institute  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Amendola","sequence":"additional","affiliation":[{"name":"Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Salducca","sequence":"additional","affiliation":[{"name":"Oncological Orthopedics Department IRCCS \u2013 Regina Elena National Cancer Institute  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Gumina","sequence":"additional","affiliation":[{"name":"Department of Anatomical, Histological, Forensic Medicine and Orthopedic Science University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2016.05.018"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301\u2010620X.105B6.BJJ\u20102022\u20100068.R2"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.8.2.365"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-010-1359-8"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198603000-00003"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199301000-00035"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-29279-2"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-022-06005-1"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1743223"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100044\u20101779652"},{"key":"e_1_2_13_12_1","first-page":"123","article-title":"Knee Resection Arthrodesis With Allograft: A Long\u2010Term Follow\u2010Up Study","volume":"88","author":"Casadei R.","year":"2003","journal-title":"Chirurgia Degli Organi di Movimento"},{"key":"e_1_2_13_13_1","first-page":"751","article-title":"Arthrodesis of the Knee With a Vascularized Fibular Rotatory Graft","volume":"77","author":"Rasmussen M. R.","year":"1995","journal-title":"Journal of Bone and Joint Surgery [Internet]"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199106000-00030"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200103000-00024"},{"key":"e_1_2_13_16_1","first-page":"7764","article-title":"Intra\u2010Articular Soft\u2010Tissue Sarcoma of the Knee: Is Extra\u2010Articular Resection and Tumor Endoprosthetic Reconstruction the Solution? A Retrospective Report on Eight Cases","volume":"11","author":"Nottrott M.","year":"2019","journal-title":"Orthopedic Reviews (Pavia) [Internet]"}],"container-title":["Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.70224","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/os.70224","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/os.70224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T09:36:49Z","timestamp":1770025009000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/os.70224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,29]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/os.70224"],"URL":"https:\/\/doi.org\/10.1111\/os.70224","archive":["Portico"],"relation":{},"ISSN":["1757-7853","1757-7861"],"issn-type":[{"value":"1757-7853","type":"print"},{"value":"1757-7861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,29]]},"assertion":[{"value":"2025-04-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}