{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T09:51:03Z","timestamp":1778925063249,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2012,10,18]],"date-time":"2012-10-18T00:00:00Z","timestamp":1350518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p><jats:bold>\n            <jats:italic>Background<\/jats:italic>\n          <\/jats:bold>:<jats:italic>Chagas' disease is an endemic disease in most Latin American countries. The cardiomyopathy associated with this condition often requires permanent pacing due to bradycardia. The aim of this study was to compare the indications for pacemaker implantation, intraoperative measurements, and long\u2010term follow\u2010up of patients with Chagas' cardiomyopathy (ChCM) and ischemic cardiomyopathy (ICM) referred for pacemaker implantation.<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Methods<\/jats:italic>\n          <\/jats:bold>: <jats:italic>Retrospective study including consecutive patients with ChCM (Group 1) and ICM (Group 2), who underwent pacemaker implantation in a single center.<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Results<\/jats:italic>\n          <\/jats:bold>: <jats:italic>We analyzed 360 patients. Patients in Group 1 were younger (66.29 \u00b1 7.01 vs 75.3 \u00b1 7.11 years; P = 0.0001) and more often male (72% vs 60%; P = 0.05). Sinus node dysfunction (SND) was more prevalent in Group 1 (70% vs 52%; P = 0.03). Atrioventricular block was less prevalent in Group 1 (30% vs 48%; P = 0.04). No significant differences were found with respect to left ventricular ejection fraction (54.2 \u00b1 9.1 vs 53.4 \u00b1 8.2%; P = NS) and baseline QRS duration (119 \u00b1 34 vs 108 \u00b1 29 ms; P = NS). Right bundle branch block was more frequent in Group 1 (44% vs 12%; P = 0.0001), and left bundle branch block in Group 2 (6% vs 22%; P = 0.0001). Implantation time was longer in Group 1 (39 \u00b1 19 vs 29 \u00b1 13 minutes; P = 0.001) and was with higher atrial and ventricular pacing thresholds (1.4 \u00b1 0.8 vs 1.0 \u00b1 0.5 V; P = 0.001 and 1.2 \u00b1 0.8 vs 0.6 \u00b1 0.8 V; P = 0.001, respectively). During a follow\u2010up of 42.8 \u00b1 13.6 months, Group 1 had a higher incidence of new atrial fibrillation (34% vs 25.5%; P = 0.001), and there was a nonsignificant trend toward more displacements of the ventricular lead (6% vs 3.5%; P = 0.3). There were no deaths during the follow\u2010up.<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Conclusions<\/jats:italic>\n          <\/jats:bold>: <jats:italic>ChCM patients receiving pacemakers are younger and more frequently have SND compared to those with ICM. Pacemaker implant is longer in patients with ChCM disease and is with higher pacing thresholds. The incidence of new atrial fibrillation during the follow\u2010up is significantly higher in patients with ChCM. (PACE 2012;35:1494\u20101497)<\/jats:italic><\/jats:p>","DOI":"10.1111\/pace.12013","type":"journal-article","created":{"date-parts":[[2012,10,19]],"date-time":"2012-10-19T00:34:24Z","timestamp":1350606864000},"page":"1494-1497","source":"Crossref","is-referenced-by-count":13,"title":["Permanent Pacing in Patients with Chagas' Disease"],"prefix":"10.1111","volume":"35","author":[{"given":"MAURICIO","family":"ARCE","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JORGE","family":"VAN GRIEKEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FRANCISCO","family":"FEMEN\u00cdA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MART\u00cdN","family":"ARRIETA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WILLIAM F.","family":"MCINTYRE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ADRIAN","family":"BARANCHUK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,18]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762002000500002"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762007005000093"},{"key":"e_1_2_7_4_2","first-page":"367","article-title":"Patogenia das manifesta\u00e7\u00f5es card\u00edacas na doen\u00e7a de Chagas","volume":"65","author":"Lopes ER","year":"1995","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_7_5_2","first-page":"534","article-title":"Chagasic cardiopathy immunopathologic and morphologic studies in myocardial biopsies","volume":"86","author":"Cossio PM","year":"1977","journal-title":"Am J Pathol"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.624296"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.2000.11813580"},{"key":"e_1_2_7_8_2","first-page":"345","article-title":"S\u00edndrome bradicardia taquicardia en la cardiopat\u00eda chag\u00e1sica cr\u00f3nica","volume":"42","author":"Lavadenz R","year":"1984","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(78)90362-9"},{"key":"e_1_2_7_10_2","first-page":"245","article-title":"Study of sinus node function and atrioventricular conduction in patients with chagas disease","volume":"52","author":"Carrasco HA","year":"1982","journal-title":"Arch Inst Cardiol Mex"},{"key":"e_1_2_7_11_2","first-page":"359","article-title":"Comparative study of the threshold in acute and chronic stimulation in patients with Chagas disease and myocardiosclerosis with cardiac pacemakers","volume":"35","author":"Gauch PR","year":"1980","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822006000300003"},{"key":"e_1_2_7_13_2","first-page":"8\u201312","article-title":"Pacemakers in patients with Chagasic cardiomyopathy. Comparison with coronary artery disease's patients","volume":"18","author":"Arce M","year":"2012","journal-title":"Salud (I) Ciencia"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa053241"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S8355"},{"key":"e_1_2_7_16_2","first-page":"99","article-title":"Diferencias cl\u00ednicas y paracl\u00ednicas entre la miocardiopatia chagasica cr\u00f3nica y las miocardiopatias dilatadas primarias","volume":"53","author":"Parada H","year":"1989","journal-title":"Arq Bras Cardiol"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpace.12013","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.12013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T17:05:38Z","timestamp":1698685538000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.12013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,18]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1111\/pace.12013"],"URL":"https:\/\/doi.org\/10.1111\/pace.12013","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,18]]}}}