{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:01:30Z","timestamp":1792094490812,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,12,17]],"date-time":"2012-12-17T00:00:00Z","timestamp":1355702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The incidence of cardiac implantable electronic device (CIED) infections has risen rapidly since 2004. A commercially available minocycline and rifampin impregnated antibacterial envelope has been associated with a low CIED infection rate. We performed a retrospective cohort study analyzing CIED infection rates in patients receiving an antibacterial envelope.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospectively applied criteria for use of the antibacterial envelope included \u22652 of the following: diabetes, renal insufficiency, anticoagulation, chronic corticosteroid use, fever or leukocytosis at the time of implantation, prior CIED infection, \u22653 leads (cardiac resynchronization therapy or abandoned leads), pacemaker dependence, or early pocket reentry. CIED infection rate was compared to a cohort of patients with matched risk factors and a CIED implanted prior to use of the antibacterial envelope.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 260 antibacterial envelopes were implanted from November 1, 2009 to April 30, 2012. The mean number of CIED infection risk factors was 2.8 \u00b1 1.2. The control cohort (N = 639) was matched for mean number of CIED infection risk factors (2.8 \u00b1 1.2), though individual risk factors differed. After a minimum of 90 days of follow\u2010up, there was one CIED infection among patients who received an antibacterial envelope (0.4%), compared to 19 (3%) in controls (odds ratio [95% confidence interval] 0.13 [0.02\u20130.95], P = 0.04). This difference persisted after adjustment for covariates (0.09 [0.01\u20130.73], P = 0.02) and propensity score matching (0.11 [0.01\u20130.85], P = 0.04).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients prospectively identified at high risk for CIED infection, use of a commercially available antibacterial envelope was associated with a marked reduction in CIED infections when compared to a matched control cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.12063","type":"journal-article","created":{"date-parts":[[2012,12,18]],"date-time":"2012-12-18T13:14:38Z","timestamp":1355836478000},"page":"354-361","source":"Crossref","is-referenced-by-count":78,"title":["Use of an Antibacterial Envelope is Associated with Reduced Cardiac Implantable Electronic Device Infections in High\u2010Risk Patients"],"prefix":"10.1111","volume":"36","author":[{"given":"MATTHEW J.","family":"KOLEK","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Vanderbilt University Medical Center  Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WILLIAM F.","family":"DRESEN","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Vanderbilt University Medical Center  Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QUINN S.","family":"WELLS","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Vanderbilt University Medical Center  Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHRISTOPHER R.","family":"ELLIS","sequence":"additional","affiliation":[{"name":"Cardiovascular Medicine Division Department of Internal Medicine Cardiac Electrophysiology Section Vanderbilt Heart and Vascular Institute  Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.05.016"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13556-011-0003-6"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2009.02670.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.033"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2003.06.005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.795906"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/518889"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2007.02.272"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2008.151985"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00307.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.678664"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00529.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.441"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.10.034"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2009.02406.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2010.02931.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2008.89"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.948828"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a010011"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.10.1187"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-133-8-200010170-00011"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.497"},{"key":"e_1_2_6_24_1","first-page":"1","article-title":"Current 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