{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:04:12Z","timestamp":1761581052939},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T00:00:00Z","timestamp":1357776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Vasovagal syncope (VS) is the most prevalent cause of transient loss of consciousness. The treatment consists of lifestyle modifications and pacemaker in some patients. The purpose of this study is to evaluate the effect of measures to compress the lower limbs in patients with recurrent episodes of VS submitted to the tilt\u2010test (TT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Twenty patients, average age 30.5 years (15\u201375), 13 (65%) female, with a clinical diagnosis of VS and previous TT with a positive result and who had at least one episode of syncope during the last year, were included in this placebo\u2010controlled randomized crossover study. The patients underwent two consecutive TT, at a 1\u2010hour interval, with and without compression by pneumatic compression boots with 40 mmHg at the heels and 30 mmHg for the legs. The blood pressure (BP) and heart rate (HR) of these patients were monitored continuously. The outcome assessors were blinded. The results of the TT were positive in 13 (65%) of the patients in the control groups and in two (10%) of the patients with compression (P &lt; 0.0001). Throughout the test, the systolic BP was not different among the groups. On the other hand, the HR measures showed a difference only in the tilted position at 2 minutes, of 73 \u00b1 16 beats per minute (bpm) in the control group and of 69 \u00b1 16 bpm (P = 0.047) in the compression group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compression of the lower limbs is very effective to render the TT negative in patients with a diagnosis of VS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.12069","type":"journal-article","created":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T21:09:54Z","timestamp":1357852194000},"page":"451-455","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy of Lower Limb Compression in the Management of Vasovagal Syncope\u2014Randomized, Crossover Study"],"prefix":"10.1111","volume":"36","author":[{"given":"RAFAEL QUEIROZ DOS","family":"SANTOS","sequence":"first","affiliation":[{"name":"Instituto de Cardiologista do Rio Grande do Sul  Porto Alegre\u2010RS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LUIS","family":"SMIDT","sequence":"additional","affiliation":[{"name":"Post\u2010graduate program in Cardiology Universidade Federal do Rio Grande do Sul  Porto Alegre\u2010RS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BRUNA HELENA","family":"SUZIGAN","sequence":"additional","affiliation":[{"name":"Medical Student at Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre\u2010RS  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LUCAS VIEIRA","family":"DE SOUZA","sequence":"additional","affiliation":[{"name":"Medical Student at Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre\u2010RS  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JUAREZ NEUHAUS","family":"BARBISAN","sequence":"additional","affiliation":[{"name":"Instituto de Cardiologista do Rio Grande do Sul  Porto Alegre\u2010RS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp298"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012407"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00257-2"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.06.052"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)24003-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.06.059"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eupc.2004.08.008"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/eupc.1999.0064"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1042\/cs0810575"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9629(15)40483-5"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-133-9-200011070-00014"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1102"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-004-0188-9"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.15.6.875"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90767-U"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.11.1452"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.5.973"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/eupc.2001.0168"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02683-9"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000030939.12646.8F"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpace.12069","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.12069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T07:05:27Z","timestamp":1700636727000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.12069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,10]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/pace.12069"],"URL":"https:\/\/doi.org\/10.1111\/pace.12069","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,10]]}}}