{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T09:46:06Z","timestamp":1774518366039,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T00:00:00Z","timestamp":1368662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2013,10]]},"abstract":"Background<\/jats:title>Multidetector computed tomography (MDCT) may be useful to identify patients with patent foramen ovale (PFO). The aim of this study was to analyze whether a MDCT performed before pulmonary vein isolation reliably detects a PFO that may be used for access to the left atrium.<\/jats:p><\/jats:sec>Methods and Results<\/jats:title>In 79 consecutive patients, who were referred for catheter ablation of symptomatic paroxysmal or persistent atrial fibrillation (AF), the presence of a PFO was explored by MDCT and transesophageal echocardiography (TEE). TEE was considered as the gold standard, and quality of TEE was good in all patients. In 16 patients (20.3%), MDCT could not be used for analysis because of artifacts, mainly because of AF. On TEE, a PFO was found in 15 (23.8%) of the 63 patients with usable MDCT. MDCT detected six PFO of which four were present on TEE. This corresponded to a sensitivity of 26.7%, a specificity of 95.8%, a negative predictive value of 80.7%, and a positive predictive value of 66.7%. The receiver operating characteristics curve of MDCT for the detection of PFO was 0.613 (95% confidence interval 0.493\u20130.732).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>MDCT may detect a PFO before pulmonary isolation. However, presence of AF may lead to artifacts on MDCT impeding a meaningful analysis. Furthermore, in this study sensitivity and positive predictive value of MDCT were low and therefore MDCT was not a reliable screening tool for detection of PFO.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.12157","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T20:54:38Z","timestamp":1368737678000},"page":"1245-1250","source":"Crossref","is-referenced-by-count":5,"title":["Impact of Cardiac Computed Tomography of the Interatrial Septum before Pulmonary Vein Isolation"],"prefix":"10.1111","volume":"36","author":[{"given":"RICHARD","family":"KOBZA","sequence":"first","affiliation":[{"name":"Division of Cardiology Luzerner Kantonsspital Luzern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANDREAS W.","family":"SCHOENENBERGER","sequence":"additional","affiliation":[{"name":"Division of Geriatrics Department of General Internal Medicine, Inselspital Bern University Hospital, and University of Bern Bern 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Biomedicine Basel University Hospital Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PAUL","family":"ERNE","sequence":"additional","affiliation":[{"name":"Division of Cardiology Luzerner Kantonsspital Luzern 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