{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T22:04:27Z","timestamp":1745359467583},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T00:00:00Z","timestamp":1384473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>To report a long\u2010term single\u2010site experience of the cut\u2010and\u2010sew Cox maze III procedure for atrial fibrillation (AF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 232 consecutive patients underwent the Cox maze III procedure for symptomatic therapy\u2010refractory AF, with concomitant surgery in 34 patients. Follow\u2010up data were obtained from electrocardiograms, patient visits, questionnaires, and medical files.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 103 patients (44%) with paroxysmal AF during 8.8 \u00b1 6.5 years and 129 patients (56%) with nonparoxysmal AF for 7.3 \u00b1 6.7 years. The preoperative New York Heart Association class was better in patients with paroxysmal AF (P &lt; 0.0001); the left ventricular ejection fraction was 59 \u00b1 7% versus 56 \u00b1 8%, P = 0.003, and the left atrial area 24 \u00b1 6 versus 27 \u00b1 6 cm<jats:sup>2<\/jats:sup>, P = 0.01. Early and late postoperative adverse events occurred at similar rates. Four patients from each group died of reasons unrelated to surgery. The mean follow\u2010up was 66 \u00b1 42 (5\u2013155) months. In total, 184\/229 (80%) patients were free of documented AF\/atrial flutter\/atrial tachycardia (AF\/AFl\/AT) off antiarrhythmic drugs (AA) and 189\/229 (83%) on or off AA. The hazard ratio (HR) for paroxysmal versus nonparoxysmal AF patients regarding documented AF\/AFl\/AT was 0.8 (95% confidence interval [CI] 0.4\u20131.4; P = 0.40). For patients without versus with concomitant surgery, the corresponding HR was 0.4 (95% CI 0.2\u20130.8; P = 0.008). Of 197 patients (89%) responding to the questionnaire, 41 had sought care for symptoms of arrhythmia, 29 of whom had documented AF\/AFl\/AT, whereas another six had other arrhythmias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cut\u2010and\u2010sew Cox maze III surgery provided long\u2010lasting high efficacy, also in patients with nonparoxysmal AF of long duration and\/or concomitant surgery, and was associated with low rates of subsequent adverse events.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.12286","type":"journal-article","created":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T22:14:11Z","timestamp":1384553651000},"page":"147-156","source":"Crossref","is-referenced-by-count":7,"title":["Low Mortality and Low Rate of Perceived and Documented Arrhythmias after Cox Maze III Surgery for Atrial Fibrillation"],"prefix":"10.1111","volume":"37","author":[{"given":"BIRGITTA 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