{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:18:01Z","timestamp":1760955481381},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,5,16]],"date-time":"2014-05-16T00:00:00Z","timestamp":1400198400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Monitoring of cerebral tissue oxygen saturation (SctO<jats:sub>2<\/jats:sub>) reflects cerebral microcirculation. We sought to characterize the decrease in SctO<jats:sub>2<\/jats:sub> during supraventricular tachycardia (SVT) and ventricular tachycardia (VT) in adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty patients (mean age: 46.3 \u00b1 18.1 years, 40% men) were included. Rapid atrial and ventricular pacing (200\/min) was used as a model for VT and SVT. Near\u2010infrared spectroscopy (NIRS) was used to measure SctO<jats:sub>2<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Atrial stimulation decreased right (P = 0.014) and left (P = 0.019) hemispheric SctO<jats:sub>2<\/jats:sub> compared to baseline. Ventricular stimulation also decreased right (P &lt; 0.001) and left (P &lt; 0.001) hemispheric SctO<jats:sub>2<\/jats:sub>. A negative correlation between age and minimal value under stimulation was found for atrial (right SctO<jats:sub>2<\/jats:sub> r = \u20130.641, P = 0.034; left SctO<jats:sub>2<\/jats:sub> r = \u20130.694, P = 0.018) and ventricular pacing (right SctO<jats:sub>2<\/jats:sub> r = \u20130.564, P = 0.01; left SctO<jats:sub>2<\/jats:sub> r = \u20130.604, P = 0.005). A positive correlation was found between left ventricular ejection fraction (LVEF) and minimal value under ventricular stimulation (right SctO<jats:sub>2<\/jats:sub> r = 0.567, P = 0.009; left SctO<jats:sub>2<\/jats:sub> r = 0.471, P = 0.036).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cerebral perfusion decreased during simulated SVT and VT and is influenced by age and LVEF. Clinicians can consider NIRS monitoring in patients during ablation procedures and in critical care. NIRS may especially be appropriate for the elderly and for patients with impaired LVEF.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.12424","type":"journal-article","created":{"date-parts":[[2014,5,16]],"date-time":"2014-05-16T08:59:04Z","timestamp":1400230744000},"page":"1159-1165","source":"Crossref","is-referenced-by-count":4,"title":["Acute Decrease of Cerebral Oxygen Saturation during Rapid Ventricular and Supraventricular Rhythm: A Pilot Study"],"prefix":"10.1111","volume":"37","author":[{"given":"ALEXANDER","family":"WUTZLER","sequence":"first","affiliation":[{"name":"Department of Cardiology Charit\u00e9 \u2013 Universitaetsmedizin Berlin  Campus Virchow\u2010Klinikum Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NATALIE","family":"OTTO","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Intensive Care Medicine Charit\u00e9 \u2013 Universitaetsmedizin Berlin  Campus Virchow\u2010Klinikum Berlin 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