{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T11:23:06Z","timestamp":1789903386855,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,7,16]],"date-time":"2014-07-16T00:00:00Z","timestamp":1405468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Ventricular ectopic beats (VEBs) are usually considered a benign condition that can be managed with conservative measures. Heart rate variability (HRV), which is one of the most important methods for assessing autonomic activity, is a noninvasive, quantitative method of analyzing autonomic effects on the heart. We aimed to investigate the risk of arrhythmia in patients with VEBs and without cardiovascular disease by using HRV parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with frequent VEBs (more than 30 times in 1 hour, according to the Lown classification) were identified. Identified patients were evaluated by 24\u2010hour ECG recording. Our study included 43 patients with frequent VEBs and 43 controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>General characteristics of the study population were similar. The LF (low frequency)\/HF (high frequency) ratio was significantly higher in the frequent VEBs group than in the control group (P &lt; 0.001). The rate of paroxysmal atrial fibrillation (PAF) was higher in the frequent VEB group than in the control group (P = 0.003). The number of VEBs was correlated with LF\/HF ratio and PAF (r = 0.339, P = 0.001 and r = 0.294, P = 0.006, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study showed that the sympathetic nervous system is dominant in young patients with VEBs and without significant comorbidities. There is a higher risk of atrial fibrillation in patients with VEBs and they should be monitored closely for atrial fibrillation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.12446","type":"journal-article","created":{"date-parts":[[2014,7,16]],"date-time":"2014-07-16T04:54:07Z","timestamp":1405486447000},"page":"1448-1454","source":"Crossref","is-referenced-by-count":18,"title":["Arrhythmia Risk Assessment Using Heart Rate Variability Parameters in Patients with Frequent Ventricular Ectopic Beats without Structural Heart Disease"],"prefix":"10.1111","volume":"37","author":[{"given":"AHMET","family":"BARUT\u00c7U","sequence":"first","affiliation":[{"name":"Department of Cardiology Faculty of Medicine \u00c7anakkale Onsekiz Mart University  \u00c7anakkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AHMET","family":"TEMIZ","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine \u00c7anakkale Onsekiz Mart University  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