{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T11:38:42Z","timestamp":1777203522842,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T00:00:00Z","timestamp":1410825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>To categorize indications of permanent pacemaker (PPM) implantation after transcatheter aortic valve implantation (TAVI), to determine predictors for conduction disturbances and to quantify the need for ventricular pacing during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We studied 97 patients (median age 83 years, 58% female) undergoing TAVI using the Medtronic CoreValve Revalving System (MCRS; Medtronic Inc., Minneapolis, MN, USA) or Edwards\u2010Sapien Valve (Edwards Lifesciences, Irvine, CA, USA). During follow\u2010up, no need for ventricular pacing was defined as &lt;1% ventricular pacing and intrinsic 1:1 atrioventricular (AV) conduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the 35 patients (36.1%) undergoing PPM implantation three indication categories were identified: (1) high\u2010grade AV block (Mobitz 2 or higher), (2) new\u2010onset left bundle branch block (LBBB) with a prolonged PR interval, and (3) new\u2010onset LBBB. The only independent predictors of high\u2010grade AV block were the use of MCRS (odds ratio [OR] 79.25; 95% confidence interval [CI] 4.57\u20131373.31) and the presence of preprocedural right bundle branch block (OR 81.95; 95% 95% CI 8.72\u2013770.46). Whereas high\u2010grade AV block resolved only in 17% of cases, none of the patients receiving a PPM due to LBBB with or without PR prolongation required ventricular pacing during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings justify early PPM implantation in patients with high\u2010grade AV block and may suggest a more conservative approach to PPM implantation in patients with new\u2010onset LBBB after TAVI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.12505","type":"journal-article","created":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T09:23:55Z","timestamp":1410859435000},"page":"1592-1601","source":"Crossref","is-referenced-by-count":37,"title":["Pacemaker Implantation and Need for Ventricular Pacing during Follow\u2010Up after Transcatheter Aortic Valve Implantation"],"prefix":"10.1111","volume":"37","author":[{"given":"CAROLA","family":"RAMAZZINA","sequence":"first","affiliation":[{"name":"Division of Cardiology 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