{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:46:59Z","timestamp":1778892419914,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T00:00:00Z","timestamp":1474329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Many patients with atrial fibrillation (AF) or atrial flutter (Aflutter) have concomitant sinus node dysfunction (SND). Ablation may result in injury to the sinus node complex or its blood supply resulting in sinus arrest and need for temporary pacing. We sought to characterize patients who develop acute SND (ASND) during\/immediately after AF\/Aflutter ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective analysis of AF\/Aflutter ablation patients between January 1, 2010 and February 28, 2015 to characterize those who required temporary pacemaker (TPM) implantation due to ASND (sinus arrest, sinus bradycardia &lt;40 beats\/min, or junctional rhythm with hemodynamic compromise) following atrial ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 2,151 patients, eight patients (&lt;0.5%) with ASND manifesting as sinus arrest (n = 2), severe sinus bradycardia (n = 2), and junctional rhythm with hemodynamic compromise (n = 4) were identified (all male, age 66 \u00b1 9.9 years, 4\/8 [50%] persistent AF). AF ablation was performed in four, atypical Aflutter in one, and AF\/Aflutter in three patients. The ablation set consisted of: pulmonary vein (PV) isolation (n = 6), roof line ablation (n = 6), mitral annulus\u2010left inferior PV line ablation (n = 5), left atrial appendage\u2010mitral annulus ablation (n = 1), cavotricuspid isthmus ablation (n = 5), and isolation or ablation near the superior vena cava (SVC, n = 4). Patients with peri\u2010SVC ablation were more likely to develop ASND (P = 0.03). All patients received TPM; six received permanent pacemaker before discharge, performed 3.5 days postablation (range 2\u20136 days). At 3\u2010month device interrogation, all patients were atrially paced &gt;50%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ASND is a rare complication of atrial ablation. It may be more common when peri\u2010SVC ablation is performed and may necessitate permanent pacemaker implantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.12934","type":"journal-article","created":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T09:16:44Z","timestamp":1471425404000},"page":"1116-1125","source":"Crossref","is-referenced-by-count":26,"title":["Acute Sinus Node Dysfunction after Atrial Ablation: Incidence, Risk Factors, and Management"],"prefix":"10.1111","volume":"39","author":[{"given":"AMMAR M.","family":"KILLU","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic  Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ERIN A.","family":"FENDER","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic  Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ABHISHEK 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