{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T23:34:49Z","timestamp":1781998489299,"version":"3.54.5"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T00:00:00Z","timestamp":1488499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The presence of left bundle branch block (LBBB) due to right ventricular pacing represents a particular challenge in properly measuring the QTc interval. In 2014, a new formula for the evaluation of QT interval in patients with LBBB was reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>145 patients with implantable cardioverter defibrillator were included in this prospective multicenter observational study. Inclusion criteria were: no permanent right ventricular stimulation, an intrinsic QRS interval of &lt;120 ms, and reduced left ventricular function. 12\u2010lead electrocardiogram recordings during intrinsic rhythm and during right ventricular threshold testing were performed. After LBBB correction using the reported Bogossian formula, the QTc interval was evaluated with Bazett's formula. The corrected QTc interval was compared in each patient with the QTc interval during intrinsic rhythm. All measurements were performed by an experienced electrophysiologist and a trainee who worked independently and in a blinded manner.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>74 patients (65 \u00b1 13 years; male n = 42) with apical and 71 patients (68 \u00b1 11 years; male n = 42) with nonapical right ventricular pacing were included in this study. The mean left ventricular ejection fraction was 40 \u00b1 13%. The QTc interval was determined to be 461 \u00b1 34 ms (modified by Bogossian's formula) in paced and 436 \u00b1 34 ms in intrinsic rhythm. The QTc interval was overestimated by \u0394QTc of 25 \u00b1 21 ms (mean deviation 5.7%) when using the Bogossian formula.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The novel Bogossian formula seems to be a reliable tool for QTc interval evaluation in patients with heart failure and right ventricular pacing. However, a slight overestimation of the QT\u2010interval must be respected.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13027","type":"journal-article","created":{"date-parts":[[2017,2,6]],"date-time":"2017-02-06T04:52:44Z","timestamp":1486356764000},"page":"409-416","source":"Crossref","is-referenced-by-count":15,"title":["Applicability of a Novel Formula (<i>Bogossian formula<\/i>) for Evaluation of the QT\u2010Interval in Heart Failure and Left Bundle Branch Block Due to Right Ventricular Pacing"],"prefix":"10.1111","volume":"40","author":[{"given":"GERRIT","family":"FROMMEYER","sequence":"first","affiliation":[{"name":"Division of Electryophysiology, Department of Cardiovascular Medicine University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HARILAOS","family":"BOGOSSIAN","sequence":"additional","affiliation":[{"name":"M\u00e4rkische Kliniken GmbH, Department of Cardiology and Angiology Klinikum L\u00fcdenscheid  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