{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T20:18:03Z","timestamp":1789589883259,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T00:00:00Z","timestamp":1507248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Visualization of left atrial (LA) anatomy using image integration modules has been associated with decreased radiation exposure and improved procedural outcome when used for guidance of pulmonary vein isolation (PVI) in atrial fibrillation (AF) ablation. We evaluated the CARTOSEG\u2122 CT Segmentation Module (Biosense Webster, Inc.) that offers a new CT\u2010specific semiautomatic reconstruction of the atrial endocardium.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The CARTOSEG\u2122 CT Segmentation Module software was assessed prospectively in 80 patients undergoing AF ablation. Using preprocedural contrast\u2010enhanced computed tomography (CE\u2010CT), cardiac chambers, coronary sinus (CS), and esophagus were semiautomatically segmented. Segmentation quality was assessed from 1 (poor) to 4 (excellent). The reconstructed structures were registered with the electroanatomic map (EAM). PVI was performed using the registered 3D images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Semiautomatic reconstruction of the heart chambers was successfully performed in all 80 patients with AF. CE\u2010CT DICOM file import, semiautomatic segmentation of cardiac chambers, esophagus, and CS was performed in 185 \u00b1 105, 18 \u00b1 5, 119 \u00b1 47, and 69 \u00b1 19 seconds, respectively. Average segmentation quality was 3.9 \u00b1 0.2, 3.8 \u00b1 0.3, and 3.8 \u00b1 0.2 for LA, esophagus, and CS, respectively.<\/jats:p><jats:p>Registration accuracy between the EAM and CE\u2010CT\u2010derived segmentation was 4.2 \u00b1 0.9 mm. Complications consisted of one perforation (1%) which required pericardiocentesis, one increased pericardial effusion treated conservatively (1%), and one early termination of ablation due to thrombus formation on the ablation sheath without TIA\/stroke (1%). All targeted PVs (n\u00a0\u00a0=\u00a0\u00a0309) were successfully isolated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The novel CT\u2010 CARTOSEG\u2122 CT Segmentation Module enables a rapid and reliable semiautomatic 3D reconstruction of cardiac chambers and adjacent anatomy, which facilitates successful and safe PVI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13189","type":"journal-article","created":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T11:04:02Z","timestamp":1505300642000},"page":"1206-1212","source":"Crossref","is-referenced-by-count":11,"title":["Validation of a novel CARTOSEG\u2122 segmentation module software for contrast\u2010enhanced computed tomography\u2010guided radiofrequency ablation in patients with atrial fibrillation"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6806-4463","authenticated-orcid":false,"given":"Hasan","family":"Imanli","sequence":"first","affiliation":[{"name":"Maryland Arrhythmia and Cardiology Imaging Group (MACIG)"},{"name":"Division of Cardiology Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaun","family":"Bhatty","sequence":"additional","affiliation":[{"name":"Maryland Arrhythmia and Cardiology Imaging Group (MACIG)"},{"name":"Division of Cardiology Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Jeudy","sequence":"additional","affiliation":[{"name":"Maryland Arrhythmia and Cardiology Imaging Group (MACIG)"},{"name":"Department of Diagnostic Radiology and Nuclear Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousra","family":"Ghzally","sequence":"additional","affiliation":[{"name":"Maryland Arrhythmia 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Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Duell","sequence":"additional","affiliation":[{"name":"Maryland Arrhythmia and Cardiology Imaging Group (MACIG)"},{"name":"Division of Cardiology Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"See","sequence":"additional","affiliation":[{"name":"Maryland Arrhythmia and Cardiology Imaging Group (MACIG)"},{"name":"Division of Cardiology Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Shorofsky","sequence":"additional","affiliation":[{"name":"Maryland Arrhythmia and Cardiology Imaging Group (MACIG)"},{"name":"Division of Cardiology Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timm M.","family":"Dickfeld","sequence":"additional","affiliation":[{"name":"Maryland Arrhythmia and Cardiology Imaging Group (MACIG)"},{"name":"Division of Cardiology 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