{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:32:25Z","timestamp":1740137545005,"version":"3.37.3"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,8]],"date-time":"2017-12-08T00:00:00Z","timestamp":1512691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>An increasing number of patients with chronic illnesses have implanted cardiac rhythm devices such as pacemakers and implantable cardioverter\u2010defibrillators (ICDs). This study was conducted to identify potentially useful predictors of in\u2010hospital cardiac arrest (I\u2010HCA) within paced electrocardiogram (ECG) signals from cardiovascular patients with implanted medical devices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective study of 17 subjects, full\u2010disclosure ECG traces prior to the time of documented I\u2010HCA were analyzed to determine R\u2010R intervals and QRS durations (QRSd).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ventricular paced QRSd prolongation was observed prior to I\u2010HCA in 10\/16 (63%) subjects. QRSd was significantly greater immediately preceding cardiac arrest than during each of the 8\u00a0hours prior to cardiac arrest (P\u00a0&lt;\u00a00.05). Heart rate changes (measured using standard deviation) within 15 minutes of cardiac arrest were significantly greater in subjects with pulseless electrical activity (PEA)\/asystolic arrest compared to those with cardiac arrests due to ventricular tachycardia\/ventricular fibrillation (VT\/VF) (10.13\u00a0vs 3.31; P<jats:italic>\u00a0\u00a0<\/jats:italic>=\u00a0\u00a00.024). Significant differences over the 8\u00a0hours preceding cardiac arrest in heart rate (74\u00a0vs 86\u00a0beats\/min; P<jats:italic>\u00a0\u00a0<\/jats:italic>=\u00a0\u00a00.002) and QRS duration (172\u00a0ms vs 137\u00a0ms; P\u00a0&lt;\u00a00.001) were observed between subjects with initial rhythms of VT\/VF and those with initial rhythms of PEA\/asystole.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patterns of diagnostic ECG features can be extracted from the telemetry data of patients with implanted medical devices prior to adverse events including I\u2010HCA. The detection of these significant changes might have an immediate prognostic impact on the timely treatment of some patients at risk of adverse events.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13223","type":"journal-article","created":{"date-parts":[[2017,10,25]],"date-time":"2017-10-25T13:58:42Z","timestamp":1508939922000},"page":"2-6","source":"Crossref","is-referenced-by-count":4,"title":["Changes in paced signals may predict in\u2010hospital cardiac arrest"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9239-2459","authenticated-orcid":false,"given":"Mina","family":"Attin","sequence":"first","affiliation":[{"name":"School of Nursing University of Rochester Medical Center  Rochester NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spencer Z.","family":"Rosero","sequence":"additional","affiliation":[{"name":"School of Medicine University of Rochester Medical Center  Rochester NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmy","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Hajim School of Engineering &amp; Applied Sciences University of Rochester  Rochester NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scot","family":"Nolan","sequence":"additional","affiliation":[{"name":"Scripps Medical Center  San Diego CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Tucker","sequence":"additional","affiliation":[{"name":"School of Nursing University of Rochester Medical Center  Rochester NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.10.019"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1111\/j.1540-8167.2012.02390.x","article-title":"QRS fragmentation and the risk of sudden cardiac death in MADIT II","volume":"23","author":"Brenyo A","year":"2012","journal-title":"J Cardiovasc Electrophysiol"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.09.009"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10877-014-9616-0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2012.03.026"},{"key":"e_1_2_7_7_1","unstructured":"SabouriazadP.Using signal processing for electrocardiogram prior to in\u2010hospital cardiac arrest. Master's thesis. San Diego California: San Diego State University;2014."},{"key":"e_1_2_7_8_1","first-page":"667","volume-title":"In Digital Image Processing","author":"Gozalez RC","year":"2007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ijcard.2009.05.002","article-title":"Ventricular paced rhythm and acute coronary ischemia","volume":"145","author":"Munclinger M","year":"2010","journal-title":"Int J Cardiol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.07.136"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.06.011"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1992.tb03099.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-006-8345-9"},{"key":"e_1_2_7_14_1","first-page":"851","article-title":"Paced left ventricular QRS width and ECG parameters predict outcome after cardiac resynchronization therapy: PPRoSPECT\u2010ECG Substudy","volume":"4","author":"Hsing JM","year":"2011","journal-title":"Circulation"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.097709"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.116.003039"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2010.02.005"},{"key":"e_1_2_7_18_1","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1016\/j.resuscitation.2016.12.022","article-title":"Clinical documentation of in\u2010hospital cardiac arrest in a large national health system","volume":"112","author":"Sukul D","year":"2017","journal-title":"Resuscitation"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpace.13223","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T07:08:04Z","timestamp":1695884884000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.13223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,8]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1111\/pace.13223"],"URL":"https:\/\/doi.org\/10.1111\/pace.13223","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"type":"print","value":"0147-8389"},{"type":"electronic","value":"1540-8159"}],"subject":[],"published":{"date-parts":[[2017,12,8]]}}}