{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:20:50Z","timestamp":1762507250729,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,28]],"date-time":"2017-12-28T00:00:00Z","timestamp":1514419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81200153"],"award-info":[{"award-number":["81200153"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2015SZ0180","2015SZ0148"],"award-info":[{"award-number":["2015SZ0180","2015SZ0148"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Nonvalvular atrial fibrillation (AF) is a common arrhythmia. The treatment strategy for AF mainly includes controlling symptoms and decreasing the rate of complications. Our study aimed to evaluate the safety and efficacy of combination treatment of catheter ablation and left atrial appendage (LAA) closure (one\u2010stop intervention) in patients with nonvalvular AF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Thirty\u2010four patients with symptomatic AF (mean CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>\u2010VASc score 4.1 \u00b1 1.3, mean HAS\u2010BLED score 3.8 \u00b1 1.2) were included. Patients first received radiofrequency\u2010based left atrial ablation, and then the Watchman device (Boston Scientific, Natick, MA, USA) or AMPLATZER Cardiac Plug (ACP) (St. Jude Medical, Inc., St. Paul, MN, USA) was implanted for LAA closure. Follow\u2010up was performed at 45 days and 3 months after LAA closure to assess for recurrence of AF and prevent stroke. Radiofrequency ablation and LAA closure were successful in 100% of patients without evidence of residual flow at the final transesophageal echocardiography evaluation. A Watchman device was implanted in 29 (85.3%) patients, and an ACP was implanted in five (14.7%) patients. No device\u2010related thrombus formation or embolization was identified at the 45\u2010day or 3\u2010month follow\u2010up. Serious complications, including death, transient ischemic attack, ischemic or hemorrhagic stroke, or major bleeding, were also not identified during the follow\u2010ups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For symptomatic patients with nonvalvular AF and a high risk of stroke, the one\u2010stop intervention is feasible, safe, and efficacious.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13250","type":"journal-article","created":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T03:22:41Z","timestamp":1512098561000},"page":"28-34","source":"Crossref","is-referenced-by-count":6,"title":["Safety and efficacy analysis of one\u2010stop intervention for treating nonvalvular atrial fibrillation"],"prefix":"10.1111","volume":"41","author":[{"given":"Hongde","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Diseases West China Hospital School of Clinic Medicine Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaijun","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases West China Hospital School of Clinic Medicine Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases West China Hospital School of Clinic Medicine Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases West China Hospital School of Clinic Medicine Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8164-9183","authenticated-orcid":false,"given":"Rui","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases West China Hospital School of Clinic Medicine Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,28]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.1056\/NEJM198204293061703"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1001\/jama.285.18.2370"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1161\/CIRCULATIONAHA.110.946806"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.1016\/j.jacc.2012.04.060"},{"doi-asserted-by":"publisher","key":"e_1_2_9_6_1","DOI":"10.1111\/j.1540-8167.2010.01799.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_7_1","DOI":"10.1161\/01.CIR.0000144459.37455.EE"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1136\/hrt.82.5.547"},{"doi-asserted-by":"publisher","key":"e_1_2_9_9_1","DOI":"10.1016\/0003-4975(95)00887-X"},{"doi-asserted-by":"publisher","key":"e_1_2_9_10_1","DOI":"10.1016\/j.jacc.2014.04.029"},{"doi-asserted-by":"publisher","key":"e_1_2_9_11_1","DOI":"10.1093\/europace\/euu039"},{"doi-asserted-by":"publisher","key":"e_1_2_9_12_1","DOI":"10.1016\/j.jacc.2010.05.061"},{"doi-asserted-by":"publisher","key":"e_1_2_9_13_1","DOI":"10.1093\/europace\/eus305"},{"doi-asserted-by":"publisher","key":"e_1_2_9_14_1","DOI":"10.1016\/j.jacc.2014.03.022"},{"doi-asserted-by":"publisher","key":"e_1_2_9_15_1","DOI":"10.1093\/europace\/euw295"},{"doi-asserted-by":"publisher","key":"e_1_2_9_16_1","DOI":"10.1161\/JAHA.112.002212"},{"doi-asserted-by":"publisher","key":"e_1_2_9_17_1","DOI":"10.1161\/CIRCULATIONAHA.110.976449"},{"doi-asserted-by":"publisher","key":"e_1_2_9_18_1","DOI":"10.1161\/CIRCULATIONAHA.112.114389"},{"key":"e_1_2_9_19_1","first-page":"14","article-title":"Combined catheter ablation for atrial fibrillation and watchmanw left atrial appendage occlusion procedures: a single center experience","volume":"5","author":"Walker DT","year":"2012","journal-title":"JAFIB"},{"doi-asserted-by":"publisher","key":"e_1_2_9_20_1","DOI":"10.1093\/europace\/eus413"},{"doi-asserted-by":"publisher","key":"e_1_2_9_21_1","DOI":"10.1016\/j.joa.2015.11.001"},{"doi-asserted-by":"publisher","key":"e_1_2_9_22_1","DOI":"10.1016\/j.jacc.2006.08.037"},{"doi-asserted-by":"publisher","key":"e_1_2_9_23_1","DOI":"10.1093\/eurheartj\/ehi583"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpace.13250","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T07:07:59Z","timestamp":1695884879000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.13250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,28]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1111\/pace.13250"],"URL":"https:\/\/doi.org\/10.1111\/pace.13250","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"type":"print","value":"0147-8389"},{"type":"electronic","value":"1540-8159"}],"subject":[],"published":{"date-parts":[[2017,12,28]]}}}