{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:09:51Z","timestamp":1761808191464,"version":"3.37.3"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T00:00:00Z","timestamp":1525046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Simultaneous cathodic\u2010anodal capture by a bipole of a cardiac resynchronization therapy (CRT) left\u2010ventricular (LV) catheter may depolarize a larger LV area than conventional multipoint pacing. We evaluated the feasibility of cathodic\u2010anodal LV stimulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 30 patients undergoing CRT with a quadripolar LV lead, we evaluated the cathodic and anodal capture threshold for each LV pole and compared QRS on electrocardiogram (ECG) during single\u2010point cathodic biventricular stimulation (S\u2010BS), multipoint BS (M\u2010BS), and cathodic\u2010anodal BS (CA\u2010BS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Anodal capture was obtained by three poles in 23\/30 patients, by two poles in five, and was not feasible in two. The mean single\u2010point anodal threshold was 3.93 V versus single\u2010point cathodic threshold of 1.95 V. On comparing ECGs, M\u2010BS and CA\u2010BS produced similar QRS wavefront activation in 90% of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CA\u2010BS is feasible and may be used in LV pacing to achieve a different wavefront of electrical activation. Further prospective studies are needed in order to verify the clinical impact of this kind of stimulation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13344","type":"journal-article","created":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T22:53:00Z","timestamp":1523400780000},"page":"597-602","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Feasibility of cathodic\u2010anodal left ventricular stimulation for alternative multisite pacing"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7517-0771","authenticated-orcid":false,"given":"Gabriele","family":"Dell'Era","sequence":"first","affiliation":[{"name":"Department of Cardiology University Hospital \u2018Maggiore della Carita`\u2019  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"De Vecchi","sequence":"additional","affiliation":[{"name":"SOC Unified Cardiology Borgosesia  Vercelli Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleonora","family":"Prenna","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital \u2018Maggiore della Carita`\u2019  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Devecchi","sequence":"additional","affiliation":[{"name":"SOC Unified Cardiology Borgosesia  Vercelli Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Degiovanni","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital \u2018Maggiore della Carita`\u2019  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Malacrida","sequence":"additional","affiliation":[{"name":"Boston Scientific Italia  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Magnani","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital \u2018Maggiore della Carita`\u2019  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eraldo","family":"Occhetta","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital \u2018Maggiore della Carita`\u2019  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Marino","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital \u2018Maggiore della Carita`\u2019  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut206"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.02.008"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-014-9891-1"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2005.00158.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eul013"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12650"},{"key":"e_1_2_7_8_1","first-page":"64","article-title":"Anodal stimulation: An underrecognized cause of nonresponders to cardiac resynchronization therapy","volume":"11","author":"Dendy KF","year":"2011","journal-title":"Indian Pacing Electrophysiol J"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur076"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2001.01165.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00466.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2015.06.016"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw046"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.894774"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(82)90003-0"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2007.00580.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.89.3.1159"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2011.00430.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.00943.x"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpace.13344","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13344","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T20:20:08Z","timestamp":1695500408000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.13344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,30]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/pace.13344"],"URL":"https:\/\/doi.org\/10.1111\/pace.13344","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"type":"print","value":"0147-8389"},{"type":"electronic","value":"1540-8159"}],"subject":[],"published":{"date-parts":[[2018,4,30]]},"assertion":[{"value":"2018-01-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}