{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T04:48:35Z","timestamp":1790052515468,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T00:00:00Z","timestamp":1527465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ventricular arrhythmias are reported to be more common in patients with obstructive sleep apnea (OSA). Preliminary evidence showed such parameters regarding ventricular repolarization as Tp\u2010e, Tp\u2010e\/QT, and Tp\u2010e\/QTc may be related with increased cardiac arrhythmias and even sudden cardiac death. The purpose of the present study was to evaluate ventricular repolarization during immediately preapnea period, apnea period, and postapnea hyperventilation period in patients with OSA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 59 patients who underwent polysomnography and were diagnosed with OSA between the years 2016\u20132017 in our hospital were included in our study. Of 59 patients (mean age: 52.51\u00a0\u00b1\u00a09.66), 28 were male and 31 were female. In all patients, Tp\u2010e interval, Tp\u2010e\/QT ratio, and Tp\u2010e\/QTc ratio, together with some other parameters, were calculated. Categorical variables were expressed as proportion and continuous variables were expressed as mean\u00a0\u00b1\u00a0standard deviation. Electrocardiogram calculations of interest were compared through preapnea, apnea, and postapnea periods using Friedman's test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Tp\u2010e interval (85.6\u00a0ms [78.3\u201395.6], 98\u00a0ms [88.5\u2013107.7], 91.2\u00a0ms [81\u201398.8], respectively; P\u00a0&lt;\u00a00.001), Tp\u2010e\/QT ratio (0.219 [0.202\u20130.237], 0.242 [0.224\u20130.269], 0.233 [0.212\u20130.246], respectively; P\u00a0&lt;\u00a00.001), and Tp\u2010e\/QTc ratio (0.210 [0.190\u20130.222], 0.233 [0.209\u20130.247], 0.212 [0.193\u20130.229], respectively; P\u00a0&lt;\u00a00.001) were significantly increased during apnea period compared to the preapnea period and significantly decreased during postapnea hyperventilation period compared to the apnea period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tp\u2010e interval, Tp\u2010e\/QT ratio, and Tp\u2010e\/QTc ratio were shown to be increased during apnea period and decreased during postapnea hyperventilation period. Our findings may help explain cardiac arrhythmias and sudden death in OSA patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13365","type":"journal-article","created":{"date-parts":[[2018,5,4]],"date-time":"2018-05-04T11:56:33Z","timestamp":1525434993000},"page":"762-766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Changes in the parameters of ventricular repolarization during preapnea, apnea, and postapnea periods in patients with obstructive sleep apnea"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8170-5912","authenticated-orcid":false,"given":"Erdo\u011fan","family":"S\u00f6kmen","sequence":"first","affiliation":[{"name":"Department of Cardiology Ahi Evran University Training and Research Hospital Kirsehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinan Cemgil","family":"\u00d6zbek","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ahi Evran University Training and Research Hospital Kirsehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"\u00c7elik","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ahi Evran University Training and Research Hospital Kirsehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serkan","family":"Sivri","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ahi Evran University Training and Research Hospital Kirsehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Metin","sequence":"additional","affiliation":[{"name":"Department Otorhinolaryngology Ahi Evran University Training and Research Hospital Kirsehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Avcu","sequence":"additional","affiliation":[{"name":"Department Otorhinolaryngology Ahi Evran University Training and Research Hospital Kirsehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.5.667"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.27.020176.002341"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09464-3"},{"key":"e_1_2_7_5_1","first-page":"1311","article-title":"Obstructive sleep apnea is a common disorder in the population\u2014a review on the epidemiology of sleep apnea","volume":"7","author":"Franklin KA","year":"2015","journal-title":"J Thorac Dis"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.189420"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/28.4.499"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1183\/09031936.00027406","article-title":"Management Committee of EU COST ACTION B26. 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