{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:02:31Z","timestamp":1773864151512,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T00:00:00Z","timestamp":1531699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Cardiac magnetic resonance (CMR)\u2010identified late gadolinium enhancement (LGE), representing regional fibrosis, is often used to predict ventricular arrhythmia risk in nonischemic cardiomyopathy (NICM). However, LGE is more closely correlated with sustained monomorphic ventricular tachycardia (SMVT) than ventricular fibrillation (VF). We characterized CMR findings of ventricular LGE in VF survivors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined consecutively resuscitated VF survivors undergoing contrast\u2010enhanced 1.5T CMR between 9\/2007 and 7\/2016. We excluded coronary artery disease, hypertrophic cardiomyopathy, amyloid, sarcoid, arrhythmogenic right ventricular cardiomyopathy, and channelopathy. Preexisting implantable cardioverter\u2010defibrillator (ICD) was a CMR contraindication. VF patients were divided into three groups: (1) NICM, (2) left ventricular (LV) dilatation with normal LV ejection fraction (LVEF), and (3) normal LV size and LVEF. Two groups of NICM patients with and without SMVT were examined for comparison.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We analyzed 87\u00a0VF patients, and found that LGE was seen in 8\/22 (36%) with NICM (LVEF 38\u00a0\u00b1\u00a011%, LV end\u2010diastolic volume index [LVEDVI] 134\u00a0\u00b1\u00a068\u00a0mL\/BSA), 11\/40 (28%) with LV dilatation and normal LVEF (LVEDVI 103\u00a0\u00b1\u00a017\u00a0mL\/BSA), 4\/25 (16%) with normal LV size and LVEF. Incidence of LGE in NICM patients without prior ventricular tachycardia\/VF (LVEF 36\u00a0\u00b1\u00a012%, LVEDVI 141\u00a0\u00b1\u00a046\u00a0mL\/body surface area [BSA]) was 117\/277 and was not lower than those with VF and NICM (42%\u00a0vs 36%; P\u00a0=\u00a00.59). By contrast, 22\/37 NICM patients with SMVT (LVEF 42\u00a0\u00b1\u00a011%, LVEDVI 123\u00a0\u00b1\u00a048\u00a0mL\/BSA) were LGE\u2010positive (59% NICM\u2010SMVT vs 36% NICM\u2010VF; P\u00a0=\u00a00.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most VF survivors with a diagnosis of NICM did not have LGE on CMR and would not have met primary prevention ICD criteria based on LVEF. Absence of LGE may not portend a benign prognosis in NICM. Novel strategies for determining SCD risk in this cohort are required.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13426","type":"journal-article","created":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T08:31:53Z","timestamp":1529656313000},"page":"1109-1115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Absence of late gadolinium enhancement on cardiac magnetic resonance imaging in ventricular fibrillation and nonischemic cardiomyopathy"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6990-302X","authenticated-orcid":false,"given":"Aleksandr","family":"Voskoboinik","sequence":"first","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital  Melbourne Australia"},{"name":"Baker Heart &amp; Diabetes Institute  Melbourne Australia"},{"name":"Heart Centre The Alfred Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C. G.","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Cardiology Western Health  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica K.","family":"Elliott","sequence":"additional","affiliation":[{"name":"Heart Centre The Alfred Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedict T.","family":"Costello","sequence":"additional","affiliation":[{"name":"Baker Heart &amp; Diabetes Institute  Melbourne Australia"},{"name":"Heart Centre The Alfred Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital  Melbourne Australia"},{"name":"Baker Heart &amp; Diabetes Institute  Melbourne Australia"},{"name":"Heart Centre The Alfred Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin A.","family":"Mariani","sequence":"additional","affiliation":[{"name":"Heart Centre The Alfred Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan M.","family":"Kalman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine University of Melbourne  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter M.","family":"Kistler","sequence":"additional","affiliation":[{"name":"Baker Heart &amp; Diabetes Institute  Melbourne Australia"},{"name":"Heart Centre The Alfred Hospital  Melbourne Australia"},{"name":"Department of Medicine University of Melbourne  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Baker Heart &amp; Diabetes Institute  Melbourne Australia"},{"name":"Heart Centre The Alfred Hospital  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph B.","family":"Morton","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine University of Melbourne  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00020-4"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90618-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01462.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.01.029"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeu182"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.06.062"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.05.032"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.018"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.11.052"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12911"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2016.01.033"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.01.014"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.07.122"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00184-3"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v6.i7.585"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.12.020"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.12.001"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1608029"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.12.021"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpace.13426","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T20:11:24Z","timestamp":1694981484000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.13426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,16]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1111\/pace.13426"],"URL":"https:\/\/doi.org\/10.1111\/pace.13426","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,16]]},"assertion":[{"value":"2018-02-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}