{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:16:36Z","timestamp":1787015796162,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T00:00:00Z","timestamp":1537920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Many patients undergoing ventricular tachycardia (VT) or premature ventricular complex (PVC) ablation receive antithrombotic medications.\u00a0 Their uninterrupted use has the potential to affect complication rates.<\/jats:p>\n                    <jats:p>We assessed the incidence of complications in a large cohort of patients undergoing these procedures, according to antithrombotic medication use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From June 2014 to June 2016, 201 VT and PVC ablations were performed at a single center. We allocated patients to three groups: (A) anticoagulation group (international normalized ratio\u00a0\u2265\u00a01.5 or non\u2010vitamin K anticoagulant or full\u2010dose low\u2010molecular\u2010weight (LMW) heparin on day of procedure); (B) antithrombotic group (antiplatelet therapy and\/or prophylactic LMW heparin on day of procedure); and (C) no antithrombotics group.\u00a0 We assessed periprocedural complication rates in each group.\u00a0 Multivariable analysis was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Group A (47 patients) had 8.5% procedural complication rate: one stroke, one pseudoaneurysm, one femoral artery occlusion, and one access site hematoma. In this group, 37 patients had femoral arterial and 18 had epicardial access.<\/jats:p>\n                    <jats:p>In Group B (46 patients), the complication rate was 6.5%: two cardiac tamponades and one pericardial effusion without compromise.<\/jats:p>\n                    <jats:p>Group C (108 patients) had a 5.6% complication rate: three cardiac tamponades (with one periprocedural death and one concomitant gastric vessel injury), one pericardial effusion without compromise, one stomach perforation, and two access site hematomas.<\/jats:p>\n                    <jats:p>Multivariable analysis did not show any significant predictors of complications, though age approached significance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Complication rates were not significantly different between groups. These findings suggest that VT and PVC ablation can be performed safely in patients with uninterrupted antithrombotic medications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.13502","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T03:43:16Z","timestamp":1537155796000},"page":"1454-1460","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Anticoagulation and the risk of complications in ventricular tachycardia and premature ventricular complex ablation"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1088-886X","authenticated-orcid":false,"given":"Jem D.","family":"Lane","sequence":"first","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Cannie","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Volkova","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Graham","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Earley","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross J.","family":"Hunter","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fakhar","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier D.","family":"Lambiase","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"},{"name":"Institute of Cardiovascular Sciences University College London  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Schilling","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Sporton","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehul","family":"Dhinoja","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Barts Heart Centre St Bartholomew's Hospital  London United 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