{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T07:16:32Z","timestamp":1784790992217,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T00:00:00Z","timestamp":1543881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006279","name":"St. Jude Medical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006279","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013410","name":"LivaNova","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007497","name":"Biosense Webster","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with adult congenital heart disease (ACHD) have an increased risk of arrhythmic and sudden cardiac death. The subcutaneous implantable cardioverter defibrillator (S\u2010ICD) provides a potentially safer alternative to transvenous ICDs in ACHD. Suitability for S\u2010ICD depends on the surface electrocardiogram (ECG), which is often abnormal in ACHD patients. This study investigates the proportion of ACHD patients who meet the screening criteria for S\u2010ICD implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A standard screening ECG was performed in 102 patients with complex ACHD (Tetralogy of Fallot, Fontan circulation, and transposition of the great arteries). This process was repeated postexercise for patients who also had an exercise test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three quarters (75.4%) of ACHD patients meet screening criteria for an S\u2010ICD with at least one suitable vector. The most common number of acceptable vectors in the eligible group was two (35% of total population). In only 12% of total population, all three vectors were suitable while only one vector was suitable in 28% of total population. The primary vector (equivalent of ECG lead III) was the most common suitable vector, found in 62% of participants who had appropriate sensing vectors. Twenty\u2010five (24.5%) patients failed to meet the S\u2010ICD screening criteria. Of these, 14 had repaired tetralogy of Fallot. A total of 92% of patients with a Fontan circulation met ECG screening criteria. Of those who had the protocol repeated following their cardiopulmonary exercise test (<jats:italic>n<\/jats:italic>\u00a0=\u00a014), only one additional patient failed to meet the eligibility criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A quarter of ACHD patients do not meet the eligibility criteria for the S\u2010ICD. However, more than 90% of patients with a Fontan circulation are suitable for an S\u2010ICD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13537","type":"journal-article","created":{"date-parts":[[2018,11,5]],"date-time":"2018-11-05T12:43:02Z","timestamp":1541421782000},"page":"65-70","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Eligibility for subcutaneous implantable cardioverter defibrillators in the adult congenital heart disease population"],"prefix":"10.1111","volume":"42","author":[{"given":"Hannah","family":"Garside","sequence":"first","affiliation":[{"name":"Department of Cardiology Queen Elizabeth Hospital  Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Leyva","sequence":"additional","affiliation":[{"name":"Department of Cardiology Queen Elizabeth Hospital  Birmingham United Kingdom"},{"name":"Aston Medical Research Institute, Aston Medical School Aston University  Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Hudsmith","sequence":"additional","affiliation":[{"name":"Department of Cardiology Queen Elizabeth Hospital  Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Marshall","sequence":"additional","affiliation":[{"name":"Department of Cardiology Queen Elizabeth Hospital  Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7160-2074","authenticated-orcid":false,"given":"Joseph","family":"de Bono","sequence":"additional","affiliation":[{"name":"Department of Cardiology Queen Elizabeth Hospital  Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02714-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2002.007138"},{"key":"e_1_2_8_4_1","first-page":"250","article-title":"Sudden death and defibrillators in transposition of the great arteries with intra\u2010atrial baffles","volume":"1","author":"Khairy P","year":"2008","journal-title":"Heart"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.05.009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCI.0b013e31829744c7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951104003063"},{"key":"e_1_2_8_8_1","first-page":"407","article-title":"Long\u2010term follow\u2010up of implantable cardioverter\u2010defibrillators in adult congenital heart disease patients: Indications and outcomes","volume":"19","author":"Santharam S","year":"2016","journal-title":"Europace"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.622076"},{"key":"e_1_2_8_10_1","article-title":"The subcutaneous defibrillator: Who stands to benefit","volume":"12","author":"European Society of Cardiology","year":"2014","journal-title":"E\u2010J Cardiol Prac"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu375"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euv325"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12343"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.04.025"},{"key":"e_1_2_8_15_1","unstructured":"Boston Scientific Corporation. (2015).Pulse Generators User Manual. EMBLEM Subcutaneous Implantable Defibrillator Marlborough MA. 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