{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T09:04:31Z","timestamp":1784019871953,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,1,4]],"date-time":"2019-01-04T00:00:00Z","timestamp":1546560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Transcatheter aortic valve replacement (TAVR) is increasingly used to treat severe aortic stenosis. A frequent complication of TAVR is high\u2010grade or complete atrioventricular (AV) block requiring a permanent pacemaker (PPM). There are little data on the long\u2010term dependency on pacing after TAVR. The objective of this study was to determine the proportion of patients receiving a PPM for high\u2010grade or complete AV block after TAVR who remain dependent on the PPM in follow\u2010up and to determine any risk factors for, particularly the effect of postballoon dilation (PBD) on, pacemaker dependency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Of 594 consecutive patients without prior PPM undergoing TAVR (81.9% balloon\u2010expandable, 18.1% self\u2010expandable valve), 67 (13.1%) received a PPM after TAVR. PPM dependency was defined as AV block with a ventricular escape rate of \u2264 40\u00a0beats\/min. Patient and procedural characteristics were examined according to PPM dependency status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 67 patients who received a PPM within 10 days after TAVR, 27\/67 (40.3%) were dependent at first follow\u2010up and only 9\/41 (21.9%) at 1 year. PPM dependency was more common after a self\u2010expanding valve (76.9%\u00a0vs 31.5%, P\u00a0&lt;\u00a00.01), in those who underwent PBD (66.7%\u00a0vs 24.4%, P\u00a0&lt;\u00a00.01), and in patients in persistent complete AV block at PPM implantation (62.5%\u00a0vs 7.4%, P\u00a0&lt;\u00a00.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Fewer than half of patients who receive a new PPM following TAVR are pacemaker dependent at early follow\u2010up (&lt;\u00a030 days). The use of self\u2010expanding valves and PBD are associated with a markedly increased risk of PPM dependency.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13579","type":"journal-article","created":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T10:38:01Z","timestamp":1544697481000},"page":"146-152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Conduction recovery following pacemaker implantation after transcatheter aortic valve replacement"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0038-9231","authenticated-orcid":false,"given":"Rachel M.","family":"Kaplan","sequence":"first","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Yadlapati","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric P.","family":"Cantey","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod S.","family":"Passman","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Gajjar","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2129-0401","authenticated-orcid":false,"given":"Bradley P.","family":"Knight","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranya","family":"Sweis","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duc T.","family":"Pham","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Churyla","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Chris","family":"Malaisrie","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles J.","family":"Davidson","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Flaherty","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Bluhm Cardiovascular Institute, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.11.033"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.11.007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2009.02552.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.02.013"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.11.002"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.03.009"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup195"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.07.026"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-015-0906-4"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.10.032"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.08.034"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.11.115"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00671-1"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivs555"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-017-1158-2"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12378"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut206"},{"key":"e_1_2_6_19_1","article-title":"2018 ACC\/AHA\/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: A report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","author":"Kusumoto FM","year":"2018","journal-title":"Heart Rhythm"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.5b02526"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.05.019"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13579","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T19:07:35Z","timestamp":1694718455000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.13579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,4]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/pace.13579"],"URL":"https:\/\/doi.org\/10.1111\/pace.13579","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,4]]},"assertion":[{"value":"2018-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}