{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:35:56Z","timestamp":1792035356417,"version":"4.4.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K08HL122526"],"award-info":[{"award-number":["K08HL122526"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Leadless pacemakers (LPMs) have been shown to have lower postoperative complications than traditional permanent pacemakers but there have been no studies on the outcomes of LPMs in patients with transcatheter heart valve replacements (THVRs). This study determined outcomes of LPMs compared to transvenous single\u2010chamber pacemakers (SCPs) post\u2010THVR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective single\u2010center study including 10 patients who received LPMs post\u2010THVR between February 2017 and August 2018 and a comparison group of 23 patients who received SCP post\u2010THVR between July 2008 and August 2018. LPM or SCP was implanted at the discretion of electrophysiologists for atrial fibrillation with slow ventricular response or sinus node dysfunction with need for single\u2010chamber pacing only.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LPMs were associated with decreased tricuspid regurgitation (<jats:italic>P\u00a0<\/jats:italic>=\u00a00.04) and decreased blood loss during implantation (7.5\u00a0\u00b1\u00a02.5\u00a0cc for LPMs vs 16.8\u00a0\u00b1\u00a03.2\u00a0cc for SCPs, <jats:italic>P\u00a0<\/jats:italic>=\u00a00.03). Five LPM patients had devices positioned in the right ventricular septum as seen on transthoracic echocardiogram. Frequency of ventricular pacing was similar between LPM and SCP groups. In the LPM group, one case was complicated by a pseudoaneurysm and one death was due to noncardiac causes. There was one pneumothorax and one pocket infection in the SCP group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this small retrospective study, LPMs were feasible post\u2010THVR and found to perform as well as SCPs, had less intraprocedural blood loss, and were associated with less tricuspid regurgitation. Further, larger studies are required to follow longer\u2010term outcomes and complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13648","type":"journal-article","created":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T12:40:07Z","timestamp":1551703207000},"page":"542-547","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Leadless pacemaker implantation: A feasible and reasonable option in transcatheter heart valve replacement patients"],"prefix":"10.1111","volume":"42","author":[{"given":"Sarah K. L.","family":"Moore","sequence":"first","affiliation":[{"name":"Department of Medicine Vagelos College of Physicians and Surgeons Columbia University  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine H.","family":"Chau","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medicine Vagelos College of Physicians and Surgeons Columbia University  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medicine Vagelos College of Physicians and Surgeons Columbia University  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Rubin","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medicine Vagelos College of Physicians and Surgeons Columbia University  New York New 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